A critical precursor frequency of donor-reactive CD4+ T cell help is required for CD8+ T cell-mediated CD28/CD154-independent rejection.
about
Update on CD40 and CD154 blockade in transplant modelsSelective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression.Renal transplantation using belatacept without maintenance steroids or calcineurin inhibitors.PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+ T cells to transplanted tissue.Antigen-specific induced Foxp3+ regulatory T cells are generated following CD40/CD154 blockade.CD28 family and chronic rejection: "to belatacept...And beyond!".CTLA4Ig prevents alloantibody formation following nonhuman primate islet transplantation using the CD40-specific antibody 3A8Overcoming the memory barrier in tolerance induction: molecular mimicry and functional heterogeneity among pathogen-specific T-cell populations.Donor-reactive T-cell stimulation history and precursor frequency: barriers to tolerance induction.Translating costimulation blockade to the clinic: lessons learned from three pathways.2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses.B cells and transplantation tolerance.Targeting co-stimulatory pathways: transplantation and autoimmunity.Clinical consequences of circulating CD28-negative T cells for solid organ transplantation.Challenges and opportunities in targeting the CD28/CTLA-4 pathway in transplantation and autoimmunity.Anti-CD40 monoclonal antibody synergizes with CTLA4-Ig in promoting long-term graft survival in murine models of transplantation.CD28 blockade induces division-dependent downregulation of interleukin-2 receptor alpha.High-frequency alloreactive T cells augment effector function of low-frequency CD8+ T-cell responses under CD28/CD154 blockade.Differential requirements of CD4(+) T-cell signals for effector cytotoxic T-lymphocyte (CTL) priming and functional memory CTL development at higher CD8(+) T-cell precursor frequency.
P2860
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P2860
A critical precursor frequency of donor-reactive CD4+ T cell help is required for CD8+ T cell-mediated CD28/CD154-independent rejection.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A critical precursor frequency ...... 8/CD154-independent rejection.
@en
type
label
A critical precursor frequency ...... 8/CD154-independent rejection.
@en
prefLabel
A critical precursor frequency ...... 8/CD154-independent rejection.
@en
P2093
P2860
P1476
A critical precursor frequency ...... 8/CD154-independent rejection.
@en
P2093
Allan D Kirk
Christian P Larsen
Mandy L Ford
Maylene E Wagener
Samantha S Hanna
Thomas C Pearson
P2860
P304
P356
10.4049/JIMMUNOL.180.11.7203
P407
P577
2008-06-01T00:00:00Z