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CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesisMolecular Mechanisms Underlying Peritoneal EMT and FibrosisRole of bone morphogenetic protein-7 in renal fibrosisRoles for CCN2 in normal physiological processesMesenchymal Conversion of Mesothelial Cells Is a Key Event in the Pathophysiology of the Peritoneum during Peritoneal DialysisPhase 1 study of anti-CTGF monoclonal antibody in patients with diabetes and microalbuminuriaTGFβ and CCN2/CTGF mediate actin related gene expression by differential E2F1/CREB activation.Gene expression programs of mouse endothelial cells in kidney development and disease.Inhibition of CTGF ameliorates peritoneal fibrosis through suppression of fibroblast and myofibroblast accumulation and angiogenesisThe CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis.New targets for treatment of diabetic nephropathy: what we have learned from animal models.Involvement of inflammation-related miR-155 and miR-146a in diabetic nephropathy: implications for glomerular endothelial injury.Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis.Connective tissue growth factor (CTGF) expression modulates response to high glucose.Therapeutic targets for treating fibrotic kidney diseasesDecorin interacts with connective tissue growth factor (CTGF)/CCN2 by LRR12 inhibiting its biological activityConnective tissue growth factor modulates adult β-cell maturity and proliferation to promote β-cell regeneration in miceElevated Urinary Connective Tissue Growth Factor in Diabetic Nephropathy Is Caused by Local Production and Tubular Dysfunction.BMP signaling and podocyte markers are decreased in human diabetic nephropathy in association with CTGF overexpression.Allelic depletion of grem1 attenuates diabetic kidney disease.Connective tissue growth factor(CCN2), a pathogenic factor in diabetic nephropathy. What does it do? How does it do it?Less Smad2 is good for you! A scientific update on coffee's liver benefits.Fibrogenesis in kidney transplantation: potential targets for prevention and therapy.Crucial Role of Mesangial Cell-derived Connective Tissue Growth Factor in a Mouse Model of Anti-Glomerular Basement Membrane Glomerulonephritis.Chronic kidney disease growth factors in renal fibrosis.Biological pathways and potential targets for prevention and therapy of chronic allograft nephropathyRenal allograft fibrosis: biology and therapeutic targets.Agonists and Antagonists of TGF-β Family Ligands.CCN2 reduction mediates protective effects of BMP7 treatment in obstructive nephropathy.Age-dependent shifts in renal response to injury relate to altered BMP6/CTGF expression and signaling.Connective tissue growth factor antagonizes transforming growth factor-β1/Smad signalling in renal mesangial cells.Matrix metalloproteinase-2-deficient fibroblasts exhibit an alteration in the fibrotic response to connective tissue growth factor/CCN2 because of an increase in the levels of endogenous fibronectin.CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis.Coding polymorphisms of bone morphogenetic protein 2 contribute to the development of childhood IgA nephropathy.Fell-Muir lecture: Connective tissue growth factor (CCN2) -- a pernicious and pleiotropic player in the development of kidney fibrosis.Design and Analysis of CCN Gene Activity Using CCN Knockout Mice Containing LacZ Reporters.BMP7 reduces inflammation and oxidative stress in diabetic tubulopathy.Structural analyses of von Willebrand factor C domains of collagen 2A and CCN3 reveal an alternative mode of binding to bone morphogenetic protein-2.Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys.Hypomethylation of the CTGF gene locus is a common feature of paediatric pre-B acute lymphoblastic leukaemia.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
CTGF inhibits BMP-7 signaling in diabetic nephropathy.
@en
type
label
CTGF inhibits BMP-7 signaling in diabetic nephropathy.
@en
prefLabel
CTGF inhibits BMP-7 signaling in diabetic nephropathy.
@en
P2093
P2860
P50
P356
P1476
CTGF inhibits BMP-7 signaling in diabetic nephropathy.
@en
P2093
Frans A van Nieuwenhoven
Jaap A Joles
Karen M Lyons
Niels Bovenschen
Noelynn Oliver
Peggy Roestenberg
Roel Goldschmeding
P2860
P304
P356
10.1681/ASN.2007111261
P577
2008-07-16T00:00:00Z