about
Biglycan is a new extracellular component of the Chordin-BMP4 signaling pathwayAugmented synthesis and differential localization of heparan sulfate proteoglycans in Duchenne muscular dystrophyDecorin core protein fragment Leu155-Val260 interacts with TGF-beta but does not compete for decorin binding to type I collagenDifferent membrane-bound forms of acetylcholinesterase are present at the cell surface of hepatocytesA novel mechanism of sequestering fibroblast growth factor 2 by glypican in lipid rafts, allowing skeletal muscle differentiationAxonal sprouting induced in the sciatic nerve by the amyloid precursor protein (APP) and other antiproteases.Syndecan-1 expression inhibits myoblast differentiation through a basic fibroblast growth factor-dependent mechanism.Inhibition of extracellular matrix assembly induces the expression of osteogenic markers in skeletal muscle cells by a BMP-2 independent mechanism.Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis.Mice long-term high-fat diet feeding recapitulates human cardiovascular alterations: an animal model to study the early phases of diabetic cardiomyopathyDecorin interacts with connective tissue growth factor (CTGF)/CCN2 by LRR12 inhibiting its biological activityACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis.RECK-Mediated β1-Integrin Regulation by TGF-β1 Is Critical for Wound Contraction in Mice.ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers.Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, MasCTGF inhibits BMP-7 signaling in diabetic nephropathy.Role of proteoglycans in the regulation of the skeletal muscle fibrotic response.Role of skeletal muscle proteoglycans during myogenesis.Wnt signaling in skeletal muscle dynamics: myogenesis, neuromuscular synapse and fibrosis.Angiotensins as therapeutic targets beyond heart disease.Transforming growth factor type-β inhibits Mas receptor expression in fibroblasts but not in myoblasts or differentiated myotubes; Relevance to fibrosis associated to muscular dystrophies.SMAD3 and SP1/SP3 Transcription Factors Collaborate to Regulate Connective Tissue Growth Factor Gene Expression in Myoblasts in Response to Transforming Growth Factor β.Angiotensin-(1-7) decreases skeletal muscle atrophy induced by angiotensin II through a Mas receptor-dependent mechanism.Transforming growth factor type beta 1 increases the expression of angiotensin II receptor type 2 by a SMAD- and p38 MAPK-dependent mechanism in skeletal muscle.Angiotensin II-induced pro-fibrotic effects require p38MAPK activity and transforming growth factor beta 1 expression in skeletal muscle cells.The internal region leucine-rich repeat 6 of decorin interacts with low density lipoprotein receptor-related protein-1, modulates transforming growth factor (TGF)-β-dependent signaling, and inhibits TGF-β-dependent fibrotic response in skeletal muscCTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy.Angiotensin II receptor type 1 blockade decreases CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles.Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis.Connective tissue growth factor induction by lysophosphatidic acid requires transactivation of transforming growth factor type β receptors and the JNK pathway.Constitutively activated dystrophic muscle fibroblasts show a paradoxical response to TGF-beta and CTGF/CCN2.Heparin activates Wnt signaling for neuronal morphogenesis.Skeletal muscle cells express the profibrotic cytokine connective tissue growth factor (CTGF/CCN2), which induces their dedifferentiation.Heparan sulfate provides a mechanism to respond to FGFR2b and control regenerative expansion.A novel modulatory mechanism of transforming growth factor-beta signaling through decorin and LRP-1.Extracellular proteoglycans modify TGF-beta bio-availability attenuating its signaling during skeletal muscle differentiation.Betaglycan induces TGF-beta signaling in a ligand-independent manner, through activation of the p38 pathway.Changes in secreted and cell associated proteoglycan synthesis during conversion of myoblasts to osteoblasts in response to bone morphogenetic protein-2: role of decorin in cell response to BMP-2.Dermatan sulfate exerts an enhanced growth factor response on skeletal muscle satellite cell proliferation and migration.Betaglycan expression is transcriptionally up-regulated during skeletal muscle differentiation. Cloning of murine betaglycan gene promoter and its modulation by MyoD, retinoic acid, and transforming growth factor-beta.
P50
Q24529120-104B0812-C6AC-4571-8B28-CD2A1CC34D71Q28215514-359C3DCB-AADD-40EC-8068-B3D005ED12B0Q28277330-0DBBB96D-07DC-4298-AAB9-2C4C2259A531Q28572173-49ACDE4C-2394-4998-BB9A-AB01418005ECQ28592424-53712DE7-C8A6-4C0E-AF73-6D1B80111FB2Q31001104-F7AA220F-E3E8-4950-A5C9-3E69B1D50651Q31971336-0010C55E-C389-48C7-A064-AA4F81ED9D3EQ33508701-548277A0-581A-4ACF-96C1-2FB8CB1AA405Q33799384-92C06A4D-CFE3-4C1E-86FA-44D76744877FQ34674362-9F7903B1-C87D-4374-8BE7-0A3EE7EEA981Q35085132-E5A1D2D2-EDFB-4CE2-9727-EBAC2050CD6EQ35138448-67D97285-415B-4671-ADA4-0B378B2A0FF3Q35738740-D3943CE7-9FCA-40AF-80E3-66D4AC9C8A7CQ36375659-A64DFE01-1D9E-432A-B36E-1FB0E865F3ACQ36856035-139AD2AD-1059-407E-BFCA-6F1A5CDD2DFFQ36949217-D2F5AE1C-8DA1-4D1F-BF6A-557B6821F84BQ38096495-A16E3B31-46F2-4BE8-BA08-3A22BC0E22F4Q38098784-4A798ED7-4C8D-48DA-AF46-7C7C4499EB60Q38135328-6E16A633-F3D6-4A6D-AE51-5E056FDFCB0CQ38408467-816B88AA-4FD6-4C5F-8115-8098DA70BA4EQ38895037-9B8C72E3-388D-49E9-A46B-0A8256A6FD69Q38905039-2EE5486D-08E1-4EF0-8CB8-FDD2BE1C27CCQ38956473-E89C1496-134A-44CD-8783-5F8495F9C335Q39185363-39C6C21B-497E-49D5-A501-312FABB9675DQ39282077-0CC2C1F6-2389-4E77-BBC1-A337EACE7CA4Q39421460-15AD8FB1-969D-471F-9F9B-B76640D2FAE6Q39493006-CC06B729-7BA1-46B9-AB72-031031A51940Q39529950-998AA2CA-5FE3-47D6-B67D-E2A4F3BD33D3Q39629598-1189D7CD-2EBE-46CB-B502-E9B0A26E12BCQ39641396-DBB60609-9A56-4A5C-A50A-F25EEE20D6AEQ39670210-6821D5A1-8382-475E-A725-616E17C49BF5Q39986552-28C6E51F-27C1-4247-8015-E9DD4CD4117DQ40038399-7066B3B2-8013-42AE-8D93-0D15E9A39390Q40095796-78E0EB73-069B-4655-BEF5-E1A14E2FFA81Q40136056-229EDF9C-EA12-4F95-8D65-D6175B678218Q40269225-CCEC9DBA-FFE5-4F39-BEBD-4A14C276F2FBQ40329472-7725848B-F468-469C-8EB9-21094F75D17DQ40416279-ABB167B6-765B-4580-899F-B7D4DF408FAAQ40619052-F730151A-9737-4C0C-941B-D2229907F90CQ40694319-3F8BC875-3902-4B3B-BA8E-7AF8516CD3E8
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Enrique Brandan
@ast
Enrique Brandan
@en
Enrique Brandan
@es
Enrique Brandan
@nl
Enrique Brandan
@sl
type
label
Enrique Brandan
@ast
Enrique Brandan
@en
Enrique Brandan
@es
Enrique Brandan
@nl
Enrique Brandan
@sl
prefLabel
Enrique Brandan
@ast
Enrique Brandan
@en
Enrique Brandan
@es
Enrique Brandan
@nl
Enrique Brandan
@sl
P1053
A-7063-2017
P106
P1153
7005853141
P21
P31
P3829
P496
0000-0002-6820-5059