EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and metastasis
about
Histone methylation modifiers in cellular signaling pathwaysHistone demethylase RBP2 is critical for breast cancer progression and metastasis.The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells.Receptor-interacting protein kinase 2 promotes triple-negative breast cancer cell migration and invasion via activation of nuclear factor-kappaB and c-Jun N-terminal kinase pathways.Breast Cancer and African Ancestry: Lessons Learned at the 10-Year Anniversary of the Ghana-Michigan Research Partnership and International Breast Registry.MicroRNA-101 targets EZH2, MCL-1 and FOS to suppress proliferation, invasion and stem cell-like phenotype of aggressive endometrial cancer cellsUbiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade.Osteoprotegerin mediates tumor-promoting effects of Interleukin-1beta in breast cancer cells.EZH2-mediated repression of GSK-3β and TP53 promotes Wnt/β-catenin signaling-dependent cell expansion in cervical carcinoma.IL-1β-induced activation of p38 promotes metastasis in gastric adenocarcinoma via upregulation of AP-1/c-fos, MMP2 and MMP9Metastatic biomarkers in synovial sarcoma.GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers.Epigenetic reprogramming in breast cancer: from new targets to new therapies.The matricellular protein CCN6 (WISP3) decreases Notch1 and suppresses breast cancer initiating cells.Targeting Enhancer of Zeste Homolog 2 as a promising strategy for cancer treatmentDeregulation of the miRNAs expression in cervical cancer: human papillomavirus implications.Ezh2, a novel target in detection and therapy of breast cancer.miR-21 modulates the effect of EZH2 on the biological behavior of human lung cancer stem cells in vitro.Expression of EZH2 in endometrial carcinoma and its effects on proliferation and invasion of endometrial carcinoma cells.Tranilast Inhibits Genes Functionally Involved in Cell Proliferation, Fibrosis, and Epigenetic Regulation and Epigenetically Induces miR-29c Expression in Leiomyoma Cells.ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer.p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasisMicroRNA-365 targets multiple oncogenes to inhibit proliferation, invasion, and self-renewal of aggressive endometrial cancer cells
P2860
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P2860
EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and metastasis
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
EZH2 inhibition decreases p38 ...... cancer motility and metastasis
@en
type
label
EZH2 inhibition decreases p38 ...... cancer motility and metastasis
@en
prefLabel
EZH2 inhibition decreases p38 ...... cancer motility and metastasis
@en
P2093
P2860
P1476
EZH2 inhibition decreases p38 ...... cancer motility and metastasis
@en
P2093
Ashley Cimino-Mathews
Celina G Kleer
Heather M Moore
Kathy A Toy
Maria E Gonzalez
Pedram Argani
P2860
P2888
P304
P356
10.1007/S10549-013-2498-X
P407
P577
2013-03-29T00:00:00Z