Phosphatidylserine containing liposomes reduce immunogenicity of recombinant human factor VIII (rFVIII) in a murine model of hemophilia A.
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Current understanding of interactions between nanoparticles and the immune systemPhosphatidylinositol containing lipidic particles reduces immunogenicity and catabolism of factor VIII in hemophilia a miceNext generation delivery system for proteins and genes of therapeutic purpose: why and how?In vitro immunogenicity risk assessment of therapeutic proteins in preclinical setting.Phosphatidylserine reduces immune response against human recombinant Factor VIII in Hemophilia A mice by regulation of dendritic cell function.Immunogenicity and pharmacokinetic studies of recombinant factor VIII containing lipid cochleates.Intravenous administration of Factor VIII-O-Phospho-L-Serine (OPLS) complex reduces immunogenicity and preserves pharmacokinetics of the therapeutic protein.Safe anticoagulation when heart and lungs are "on vacation".Effect of pegylated phosphatidylserine-containing liposomes in experimental chronic arthritisPEGylation of a factor VIII-phosphatidylinositol complex: pharmacokinetics and immunogenicity in hemophilia A mice.Understanding the immunogenicity and antigenicity of nanomaterials: Past, present and future.Exposure to factor VIII protein in the presence of phosphatidylserine induces hypo-responsiveness toward factor VIII challenge in hemophilia A mice.Immunogenicity of subcutaneously administered therapeutic proteins--a mechanistic perspective.Delivery of therapeutic proteins.Phosphatidylserine Converts Immunogenic Recombinant Human Acid Alpha-Glucosidase to a Tolerogenic Form in a Mouse Model of Pompe Disease.Effect of Biophysical Properties of Phosphatidylserine Particle on Immune Tolerance Induction Toward Factor VIII in a Hemophilia A Mouse Model.Binding of Factor VIII to Lipid Nanodiscs Increases its Clotting Function in a Mouse Model of Hemophilia A.Soy Phosphatidylinositol-Containing Lipid Nanoparticle Prolongs the Plasma Survival and Hemostatic Efficacy of B-domain-Deleted Recombinant Canine Factor VIII in Hemophilia A Dogs.Nanoparticles for the Induction of Antigen-Specific Immunological Tolerance.Phosphatidylserine is not just a cleanup crew but also a well-meaning teacher.
P2860
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P2860
Phosphatidylserine containing liposomes reduce immunogenicity of recombinant human factor VIII (rFVIII) in a murine model of hemophilia A.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Phosphatidylserine containing ...... murine model of hemophilia A.
@en
type
label
Phosphatidylserine containing ...... murine model of hemophilia A.
@en
prefLabel
Phosphatidylserine containing ...... murine model of hemophilia A.
@en
P2093
P2860
P921
P356
P1476
Phosphatidylserine containing ...... murine model of hemophilia A.
@en
P2093
Donald E Mager
Karthik Ramani
Razvan D Miclea
Robert M Straubinger
Sathy V Balu-Iyer
Vivek S Purohit
P2860
P304
P356
10.1002/JPS.21102
P407
P577
2008-04-01T00:00:00Z