Multidrug resistance-associated protein 1 as a major mediator of basal and apoptotic glutathione release
about
Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosisTargeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance.The synthesis and characterization of cellular membrane affinity chromatography columns for the study of human multidrug resistant proteins MRP1, MRP2 and human breast cancer resistant protein BCRP using membranes obtained from Spodoptera frugiperdaSchistosoma mansoni express higher levels of multidrug resistance-associated protein 1 (SmMRP1) in juvenile worms and in response to praziquantelVolume-sensitive anion channels mediate osmosensitive glutathione release from rat thymocytes.Mechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH effluxA phase II study on safety and efficacy of high-dose N-acetylcysteine in patients with cystic fibrosis.Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules.Glutathione and modulation of cell apoptosis.Glutathione efflux and cell death.LOSS of Mrp1 alters detoxification enzyme expression in a tissue- and hormonal-status-specific manner.Regional variations of antioxidant capacity and oxidative stress responses in HIV-1 transgenic rats with and without methamphetamine administration.Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiologyGlutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1.ABC transporters in human lymphocytes: expression, activity and role, modulating factors and consequences for antiretroviral therapies.Cancer cell resistance mechanisms: a mini review.Increased expression of the multidrug resistance-associated protein 1 (MRP1) in kidney glomeruli of streptozotocin-induced diabetic rats.
P2860
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P2860
Multidrug resistance-associated protein 1 as a major mediator of basal and apoptotic glutathione release
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Multidrug resistance-associate ...... apoptotic glutathione release
@en
type
label
Multidrug resistance-associate ...... apoptotic glutathione release
@en
prefLabel
Multidrug resistance-associate ...... apoptotic glutathione release
@en
P2860
P1476
Multidrug resistance-associate ...... apoptotic glutathione release
@en
P2093
Christine L Hammond
Nazzareno Ballatori
P2860
P304
P356
10.1016/J.BBAMEM.2008.06.011
P407
P577
2008-06-21T00:00:00Z