Antiatherosclerotic effects of a novel synthetic tissue-selective steroidal liver X receptor agonist in low-density lipoprotein receptor-deficient mice.
about
Liver X receptors at the intersection of lipid metabolism and atherogenesisStructural overview of the nuclear receptor superfamily: insights into physiology and therapeutics.LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouseDifferential effects of activation of liver X receptor on plasma lipid homeostasis in wild-type and lipoprotein clearance-deficient miceRole of Intestinal LXRα in Regulating Post-prandial Lipid Excursion and Diet-Induced Hypercholesterolemia and Hepatic Lipid Accumulation.The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis.Liver x receptor signaling pathways and atherosclerosis.A novel potent synthetic steroidal liver X receptor agonist lowers plasma cholesterol and triglycerides and reduces atherosclerosis in LDLR(-/-) miceSynthetic LXR agonist suppresses endogenous cholesterol biosynthesis and efficiently lowers plasma cholesterol.Apolipoprotein D Transgenic Mice Develop Hepatic Steatosis through Activation of PPARγ and Fatty Acid Uptake.Stimulation of Liver X Receptor Has Potent Anti-HIV Effects in a Humanized Mouse Model of HIV Infection.Ligands of Therapeutic Utility for the Liver X Receptors.Liver X receptor agonist modulation of cholesterol efflux in mice with intestine-specific deletion of microsomal triglyceride transfer proteinABC transporters, atherosclerosis and inflammation.Liver X receptor modulators: a review of recently patented compounds (2007 - 2009).Lipid-sensing nuclear receptors in the pathophysiology and treatment of the metabolic syndrome.Therapeutic strategies to deplete macrophages in atherosclerotic plaques.Liver X receptors, atherosclerosis and inflammation.Liver X receptor modulators: a review of recently patented compounds (2009 - 2012).Intestinal nuclear receptors in HDL cholesterol metabolism.LXR agonist increases apoE secretion from HepG2 spheroid, together with an increased production of VLDL and apoE-rich large HDLThe challenges and promise of targeting the Liver X Receptors for treatment of inflammatory disease.Liver X receptor activation induces apoptosis of melanoma cell through caspase pathway.Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages.
P2860
Q28082452-77BB27FE-3993-449A-91B7-57968C20867EQ30418832-017399D5-E083-4890-978D-49E32524C9D2Q30491802-5F8AE6AD-A594-486C-8B6C-E50FA8AEA11EQ33618282-73DE56A9-0529-45A6-B4AB-90C43EC903DEQ33650363-43287A79-C00F-4185-AC9F-49C6FAB68AABQ33653635-F84FC635-B3BE-4A61-98F0-1EFB78766DC7Q34056326-71FADC47-02FA-45BF-B9F6-EE4A1018EA6CQ34837806-20B96697-74FB-45AB-A1E5-F4C39A62A25AQ35185212-A646086B-9501-44DD-A0A9-D6A0F06E359EQ35665721-CEA483A2-7733-4AAF-8AB4-6F629116621CQ35962036-086AA6F5-5053-41FF-A755-15FE651D0622Q36244293-E4FCD1AA-DA87-4494-8118-745DD462B2F0Q36747243-A40F5855-2EC5-4957-ABD1-50F2DC8FF224Q37688500-DEB50236-6357-4DFD-B520-34862E14087AQ37714905-10CA4321-0A43-43A1-89EC-5A0B12A4A17CQ37900938-EA03E8BD-2FA1-4FF0-B162-9D729A0EE0A3Q37981725-88A44B2C-A8BF-4FE2-9B55-A941DC593A7BQ37993787-8E0613A9-3F32-4B3F-AD7B-1BC91D72BF60Q38119248-B89172DE-DBD2-4C0E-91A2-4D544A87EB30Q38234847-994ACD74-B4EE-4261-BAEA-D1184D146DEEQ38503442-8EE5D752-FD16-49C5-8561-27D8DB538794Q39442545-4D3BF9BF-F05C-4FAC-B33E-F9D5409525D1Q41996704-B8DF54C7-D4EE-486E-B8CA-B9C94295D4E2Q52720528-B340277F-8AB0-482A-AF6B-1E274ADE4D56
P2860
Antiatherosclerotic effects of a novel synthetic tissue-selective steroidal liver X receptor agonist in low-density lipoprotein receptor-deficient mice.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Antiatherosclerotic effects of ...... otein receptor-deficient mice.
@en
type
label
Antiatherosclerotic effects of ...... otein receptor-deficient mice.
@en
prefLabel
Antiatherosclerotic effects of ...... otein receptor-deficient mice.
@en
P2093
P2860
P356
P1476
Antiatherosclerotic effects of ...... otein receptor-deficient mice.
@en
P2093
Catherine A Reardon
Dacheng Peng
Godfrey S Getz
Richard A Hiipakka
Shutsung Liao
P2860
P304
P356
10.1124/JPET.108.142687
P407
P577
2008-08-22T00:00:00Z