Detection of multiple globin monoadducts and cross-links after in vitro exposure of rat erythrocytes to S-(1,2-dichlorovinyl)-L-cysteine sulfoxide and after in vivo treatment of rats with S-(1,2-dichlorovinyl)-L-cysteine sulfoxide
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Role of reactive metabolites in the circulation in extrahepatic toxicityMass spectral analyses of hydroxymethylvinyl ketone-hemoglobin adducts formed after in vivo exposure of Sprague-Dawley rats to 3-butene-1,2-diol.Cysteine conjugate beta-lyase activity of rat erythrocytes and formation of beta-lyase-derived globin monoadducts and cross-links after in vitro exposure of erythrocytes to S-(1,2-dichlorovinyl)-L-cysteineN-biotinyl-S-(1,2-dichlorovinyl)-L-cysteine sulfoxide as a potential model for S-(1,2-dichlorovinyl)-L-cysteine sulfoxide: characterization of stability and reactivity with glutathione and kidney proteins in vitro.Alcohol dehydrogenase- and rat liver cytosol-dependent bioactivation of 1-chloro-2-hydroxy-3-butene to 1-chloro-3-buten-2-one, a bifunctional alkylating agent.Characterization of the chemical reactivity and nephrotoxicity of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine sulfoxide, a potential reactive metabolite of trichloroethyleneGlobin monoadducts and cross-links provide evidence for the presence of S-(1,2-dichlorovinyl)-L-cysteine sulfoxide, chlorothioketene, and 2-chlorothionoacetyl chloride in the circulation in rats administered S-(1,2-dichlorovinyl)-L-cysteine.
P2860
Q26849288-C6CF6C41-6AF5-4BA3-8E46-8DABB164CB50Q33439915-4C27C6B4-F3BD-417B-AF5A-D3DCCFDCF9ADQ33477570-539FFF0C-2800-4706-8005-006B766F3A43Q35580543-167EDC63-C368-49A6-AA17-E54844192061Q36467345-EE1982A1-D706-4F9A-A844-64C575BF0039Q36569475-13490BA8-FBBB-4843-BFF6-711092F50B12Q37359661-5F238DA1-C612-407D-B09E-6BD8D9656D8A
P2860
Detection of multiple globin monoadducts and cross-links after in vitro exposure of rat erythrocytes to S-(1,2-dichlorovinyl)-L-cysteine sulfoxide and after in vivo treatment of rats with S-(1,2-dichlorovinyl)-L-cysteine sulfoxide
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Detection of multiple globin m ...... orovinyl)-L-cysteine sulfoxide
@en
type
label
Detection of multiple globin m ...... orovinyl)-L-cysteine sulfoxide
@en
prefLabel
Detection of multiple globin m ...... orovinyl)-L-cysteine sulfoxide
@en
P2860
P356
P1476
Detection of multiple globin m ...... orovinyl)-L-cysteine sulfoxide
@en
P2093
Adnan A Elfarra
Nella Barshteyn
P2860
P304
P356
10.1021/TX800060Z
P577
2008-08-06T00:00:00Z