Activation of the cellular DNA damage response in the absence of DNA lesions.
about
P1343
Multiple ATR-Chk1 pathway proteins preferentially associate with checkpoint-inducing DNA substratesCollaborator of ARF (CARF) regulates proliferative fate of human cells by dose-dependent regulation of DNA damage signalingThe AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaksRNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AXATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaksDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsAlternative cyclin D1 splice forms differentially regulate the DNA damage responseCommon mechanisms of PIKK regulationNovel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET RadiationChromatin perturbations during the DNA damage response in higher eukaryotesNot All DDRs Are Created Equal: Non-Canonical DNA Damage ResponsesThe DNA damage response induced by infection with human cytomegalovirus and other virusesSources of DNA double-strand breaks and models of recombinational DNA repairDNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choiceMolecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndromeNanoscale histone localization in live cells reveals reduced chromatin mobility in response to DNA damage.The DNA Damage Response: Making It Safe to Play with KnivesInhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signalingThe genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1Pseudo-DNA damage response in senescent cellsDouble strand break repair functions of histone H2AXNuclear accumulation of the papillomavirus E1 helicase blocks S-phase progression and triggers an ATM-dependent DNA damage responseATR: an essential regulator of genome integrityH2AX is required for cell cycle arrest via the p53/p21 pathwayAutophosphorylation and ATM activation: additional sites add to the complexity.Lysosome-mediated processing of chromatin in senescence.Positive regulation of DNA double strand break repair activity during differentiation of long life span cells: the example of adipogenesisRetinoblastoma loss modulates DNA damage response favoring tumor progressionReconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling.Histone variants: emerging players in cancer biology.Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing.Charting the landscape of tandem BRCT domain-mediated protein interactions.An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells.Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndromeAn E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus.Cyclin D1 integrates estrogen-mediated DNA damage repair signaling.Sequential and ordered assembly of a large DNA repair complex on undamaged chromatin.Systemic DNA damage accumulation under in vivo tumor growth can be inhibited by the antioxidant TempolThe viral oncoprotein tax sequesters DNA damage response factors by tethering MDC1 to chromatin.Tumors induce complex DNA damage in distant proliferative tissues in vivo
P2860
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P2860
Activation of the cellular DNA damage response in the absence of DNA lesions.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Activation of the cellular DNA damage response in the absence of DNA lesions.
@en
type
label
Activation of the cellular DNA damage response in the absence of DNA lesions.
@en
prefLabel
Activation of the cellular DNA damage response in the absence of DNA lesions.
@en
P2860
P356
P1433
P1476
Activation of the cellular DNA damage response in the absence of DNA lesions.
@en
P2093
Evi Soutoglou
Tom Misteli
P2860
P304
P356
10.1126/SCIENCE.1159051
P407
P4510
P577
2008-05-15T00:00:00Z