Differentiation of regulatory Foxp3+ T cells in the thymic cortex.
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Regulatory T-Cell Development in the Human ThymusCellular and molecular determinants for the development of natural and induced regulatory T cellsNature and nurture in Foxp3(+) regulatory T cell development, stability, and functionRegulatory T-cells: diverse phenotypes integral to immune homeostasis and suppressionTrypanosoma cruzi Experimental Infection Impacts on the Thymic Regulatory T Cell CompartmentPremature expression of Foxp3 in double-negative thymocytesCCR6 supports migration and differentiation of a subset of DN1 early thymocyte progenitors but is not required for thymic nTreg developmentH2 control of natural T regulatory cell frequency in the lymph node correlates with susceptibility to day 3 thymectomy-induced autoimmune diseaseVagaries of fluorochrome reporter gene expression in Foxp3+ regulatory T cells.DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration.Affinity-based selection of regulatory T cells occurs independent of agonist-mediated induction of Foxp3 expressionThymocyte deletion can bias Treg formation toward low-abundance self-peptide.Progressive Changes in CXCR4 Expression That Define Thymocyte Positive Selection Are Dispensable For Both Innate and Conventional αβT-cell DevelopmentDifferential requirement for CCR4 and CCR7 during the development of innate and adaptive αβT cells in the adult thymus.Extra-thymically induced regulatory T cells: do they have potential in disease prevention?Identification of an immediate Foxp3(-) precursor to Foxp3(+) regulatory T cells in peripheral lymphoid organs of nonmanipulated mice.Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cellsRare development of Foxp3+ thymocytes in the CD4+CD8+ subsetDevelopment of thymically derived natural regulatory T cells.Global mapping of H3K4me1 and H3K4me3 reveals the chromatin state-based cell type-specific gene regulation in human Treg cellsDistinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymusThe same self-peptide selects conventional and regulatory CD4⁺ T cells with identical antigen receptors.Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia.Dendritic cells in the thymus contribute to T-regulatory cell induction.How tolerogenic dendritic cells induce regulatory T cellsEpithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathwayBecoming self-aware: the thymic education of regulatory T cells.CD8α+ plasmacytoid precursor DCs induce antigen-specific regulatory T cells that enhance HSC engraftment in vivo.Immunological considerations in in utero hematopoetic stem cell transplantation (IUHCT)The requirements for natural Th17 cell development are distinct from those of conventional Th17 cellsThe molecular mechanisms of Foxp3 gene regulation.Regulatory T cells for tolerance therapy: revisiting the concept.MUCOSAL IMMUNOLOGY. Individual intestinal symbionts induce a distinct population of RORγ⁺ regulatory T cells.The Role of Dendritic Cells in Central ToleranceCutting edge: Hematopoietic-derived APCs select regulatory T cells in thymus.Tolerance and lymphoid organ structure and function.Human thymus medullary epithelial cells promote regulatory T-cell generation by stimulating interleukin-2 production via ICOS ligandLoss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency.Depletion of fat-resident Treg cells prevents age-associated insulin resistance.Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3.
P2860
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P2860
Differentiation of regulatory Foxp3+ T cells in the thymic cortex.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Differentiation of regulatory Foxp3+ T cells in the thymic cortex.
@en
type
label
Differentiation of regulatory Foxp3+ T cells in the thymic cortex.
@en
prefLabel
Differentiation of regulatory Foxp3+ T cells in the thymic cortex.
@en
P2093
P2860
P356
P1476
Differentiation of regulatory Foxp3+ T cells in the thymic cortex.
@en
P2093
Adrian Liston
Alexander Y Rudensky
Andrew G Farr
Jeffery P Rasmussen
Jennifer M Lund
Katherine M Nutsch
Pandelakis A Koni
P2860
P304
11903-11908
P356
10.1073/PNAS.0801506105
P407
P577
2008-08-11T00:00:00Z