Human DNA polymerase eta activity and translocation is regulated by phosphorylation.
about
Interferon regulatory factor 1 transactivates expression of human DNA polymerase η in response to carcinogen N-methyl-N'-nitro-N-nitrosoguanidineSeparate roles of structured and unstructured regions of Y-family DNA polymerasesRegulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteinsEvidence for a Rad18-independent frameshift mutagenesis pathway in human cell-free extractsN-Aroyl indole thiobarbituric acids as inhibitors of DNA repair and replication stress response polymerases.Variations on a theme: eukaryotic Y-family DNA polymerasesSphingosine, a modulator of human translesion DNA polymerase activityATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage.Expression of DNA translesion synthesis polymerase η in head and neck squamous cell cancer predicts resistance to gemcitabine and cisplatin-based chemotherapy.FF483-484 motif of human Polη mediates its interaction with the POLD2 subunit of Polδ and contributes to DNA damage toleranceMolecular chaperone Hsp90 regulates REV1-mediated mutagenesis.c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forksAblation of XP-V gene causes adipose tissue senescence and metabolic abnormalities.Enhancement of human DNA polymerase η activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome proteinThe Functions of Serine 687 Phosphorylation of Human DNA Polymerase η in UV Damage Tolerance.Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA.RAD18 polymorphisms are associated with platinum-based chemotherapy toxicity in Chinese patients with non-small cell lung cancer.TRIP/NOPO E3 ubiquitin ligase promotes ubiquitylation of DNA polymerase η.DNA polymerase eta and chemotherapeutic agents.Pirh2 E3 ubiquitin ligase monoubiquitinates DNA polymerase eta to suppress translesion DNA synthesis.Maintenance of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases.The Translesion Polymerase Pol η Is Required for Efficient Epstein-Barr Virus Infectivity and Is Regulated by the Viral Deubiquitinating Enzyme BPLF1.Loss of Genome Fidelity: Beta HPVs and the DNA Damage Response.Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis.Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer.Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle.Maneuvers on PCNA Rings during DNA Replication and Repair
P2860
Q24306282-DDFC49FE-D4F8-4F39-80CB-979289C36345Q24630493-B72C26CA-439F-4F15-889A-689F5D96E461Q28087183-3E51772D-4E1E-4E15-AF91-6725F2B16E09Q28482844-D628928D-EFDF-458A-9FF0-904FB2E89A86Q31117517-48E68445-6F85-43E9-BB6A-54B0BAD6CB2FQ33756190-B7615027-9E15-421C-A31C-E04BFE78AB8EQ33985368-60ECB66D-C6D5-433D-8148-4ED50240F9F1Q34159485-1F134DCA-E144-48AE-9478-D6C1C1F049C2Q35078304-2115A02C-80C7-4896-8047-C7606D1058D3Q35131140-162075E6-61ED-4861-9AB1-CC3875B891F9Q35139973-AE9A74A6-CAFB-4B80-97F2-4AD5FF75D004Q35953858-FED96E8B-5A11-46DD-8D54-B091A96342CAQ35989743-65C57B25-8215-4A99-8A34-7EF06E852FD7Q36452037-876E7E66-AA1E-41C8-B776-6809946EDC96Q37372299-9140A18D-7C23-4868-A966-56342CAA51A6Q37396238-AE75C96F-DE2A-4039-9E8B-3C25CA8FB936Q37399367-7E77F13E-7BB4-49A6-827E-6A39F67314C5Q37618680-31D78AAF-FDCC-4F91-A734-B64DD8CBB7CFQ37807048-E01ACA56-D5C4-4B9A-8DF7-92D37F0BFB1DQ38630697-0461933B-1232-45EB-9943-54019A5994FBQ39031967-3419DE1D-42E3-4C5E-8BE9-4C300E680A26Q40116028-84C0B063-1ACF-4F33-8EBC-9DFB048392C8Q45393476-87E64FCE-51F7-4A78-BD58-F91BC43E57ABQ47104269-200FF904-B560-41A8-A56F-8132CE915EB0Q47137568-FC5261F2-BB25-4703-BB35-B682827E3FF5Q47766813-838E5085-EE7E-4F33-9A88-D20F4B0F7679Q58768271-9E914E73-404A-4ED2-ABB0-ACC648607EB0
P2860
Human DNA polymerase eta activity and translocation is regulated by phosphorylation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Human DNA polymerase eta activity and translocation is regulated by phosphorylation.
@en
type
label
Human DNA polymerase eta activity and translocation is regulated by phosphorylation.
@en
prefLabel
Human DNA polymerase eta activity and translocation is regulated by phosphorylation.
@en
P2093
P2860
P356
P1476
Human DNA polymerase eta activity and translocation is regulated by phosphorylation.
@en
P2093
James E Cleaver
Jang-Yang Chang
Kai-Ming Chou
Richard E Honkanen
Yih-Wen Chen
Zafer Hatahet
P2860
P304
16578-16583
P356
10.1073/PNAS.0808589105
P407
P577
2008-10-22T00:00:00Z