Integration of human immunodeficiency virus DNA: adduct interference analysis of required DNA sites
about
Coupled integration of human immunodeficiency virus type 1 cDNA ends by purified integrase in vitro: stimulation by the viral nucleocapsid proteinChromosome structure and human immunodeficiency virus type 1 cDNA integration: centromeric alphoid repeats are a disfavored target.Rescue of multiple viral functions by a second-site suppressor of a human immunodeficiency virus type 1 nucleocapsid mutation.Transposase makes critical contacts with, and is stimulated by, single-stranded DNA at the P element termini in vitro.Metal binding by the D,DX35E motif of human immunodeficiency virus type 1 integrase: selective rescue of Cys substitutions by Mn2+ in vitroProcessing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type-1 integrase.Methylphosphonodiester substitution near the conserved CA dinucleotide in the HIV LTR alters both extent of 3'-processing and choice of nucleophile by HIV-1 integrase.A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitroDifferent roles of bases within the integration signal sequence of human immunodeficiency virus type 1 in vitro.Substrate specificity of Ty1 integrase.Influence of subterminal viral DNA nucleotides on differential susceptibility to cleavage by human immunodeficiency virus type 1 and visna virus integrases.HIV DNA integration.Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc bindingGenome-wide analysis of retroviral DNA integration.Retroviral integration: in vitro host site selection by avian integrase.The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding.The phage Mu transpososome core: DNA requirements for assembly and function.Tn 10 transposition in vivo: temporal separation of cleavages at the two transposon ends and roles of terminal basepairs subsequent to interaction of endsDNA substrate requirements for different activities of the human immunodeficiency virus type 1 integrase protein.Substrate features important for recognition and catalysis by human immunodeficiency virus type 1 integrase identified by using novel DNA substrates.Effect of DNA modifications on DNA processing by HIV-1 integrase and inhibitor binding: role of DNA backbone flexibility and an open catalytic site.Position-specific suppression and enhancement of HIV-1 integrase reactions by minor groove benzo[a]pyrene diol epoxide deoxyguanine adducts: implications for molecular interactions between integrase and substrates.On the general theory of the origins of retroviruses.Structure-based mutational analysis of the C-terminal DNA-binding domain of human immunodeficiency virus type 1 integrase: critical residues for protein oligomerization and DNA binding.Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions.Determinants of the establishment of human immunodeficiency virus type 1 latency.Human immunodeficiency virus type 1 DNA integration: fine structure target analysis using synthetic oligonucleotides.Conserved residues Pro-109 and Asp-116 are required for interaction of the human immunodeficiency virus type 1 integrase protein with its viral DNA substrate.Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop.Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors.
P2860
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P2860
Integration of human immunodeficiency virus DNA: adduct interference analysis of required DNA sites
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Integration of human immunodef ...... analysis of required DNA sites
@en
type
label
Integration of human immunodef ...... analysis of required DNA sites
@en
prefLabel
Integration of human immunodef ...... analysis of required DNA sites
@en
P2860
P356
P1476
Integration of human immunodef ...... analysis of required DNA sites
@en
P2093
P2860
P304
P356
10.1073/PNAS.89.8.3458
P407
P577
1992-04-01T00:00:00Z