Roles of integrin activation in eosinophil function and the eosinophilic inflammation of asthma.
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Interaction of eosinophils with endothelial cells is modulated by prostaglandin EP4 receptorsActivation states of blood eosinophils in asthmaPARP inhibition in leukocytes diminishes inflammation via effects on integrins/cytoskeleton and protects the blood-brain barrier.Integrins are Mechanosensors That Modulate Human Eosinophil Activation.Eosinophils in fungus-associated allergic pulmonary diseaseEosinophil-expressed galectin-3 regulates cell trafficking and migrationAbsence of alpha 4 but not beta 2 integrins restrains development of chronic allergic asthma using mouse genetic modelsGeniposide inhibits high glucose-induced cell adhesion through the NF-kappaB signaling pathway in human umbilical vein endothelial cells.Inhibition of Pyk2 blocks airway inflammation and hyperresponsiveness in a mouse model of asthma.Eosinophil Activation Status in Separate Compartments and Association with AsthmaHuman airway eosinophils respond to chemoattractants with greater eosinophil-derived neurotoxin release, adherence to fibronectin, and activation of the Ras-ERK pathway when compared with blood eosinophils.Eosinophils in the blood of hematopoietic stem cell transplanted patients are activated and have different molecular marker profiles in acute and chronic graft-versus-host diseaseHelicobacter pylori outer membrane vesicle proteins induce human eosinophil degranulation via a β2 Integrin CD11/CD18- and ICAM-1-dependent mechanism.Activation of beta1 integrins on blood eosinophils by P-selectin.Platelet activation, P-selectin, and eosinophil β1-integrin activation in asthmaGlycogen synthase kinase 3β inhibition prevents monocyte migration across brain endothelial cells via Rac1-GTPase suppression and down-regulation of active integrin conformation.Lactoferrin regulates an axis involving CD11b and CD49d integrins and the chemokines MIP-1α and MCP-1 in GM-CSF-treated human primary eosinophils.Anti-IL-5 attenuates activation and surface density of β(2) -integrins on circulating eosinophils after segmental antigen challenge.Integrin activation States and eosinophil recruitment in asthma.α(M)β(2) integrin-mediated adhesion and motility of IL-5-stimulated eosinophils on periostin.Up-regulation and activation of eosinophil integrins in blood and airway after segmental lung antigen challenge.RNA interference against interleukin-5 attenuates airway inflammation and hyperresponsiveness in an asthma model.The extracellular matrix protein mindin regulates trafficking of murine eosinophils into the airspace.Selective activation of cannabinoid receptor 2 in leukocytes suppresses their engagement of the brain endothelium and protects the blood-brain barrierAutotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation.Suppression of Eosinophil Integrins Prevents Remodeling of Airway Smooth Muscle in Asthma.Melanoma stem cells and metastasis: mimicking hematopoietic cell trafficking?Understanding eosinophilic esophagitis: the cellular and molecular mechanisms of an emerging disease.Role of leukotrienes on protozoan and helminth infections.Interaction between allergic asthma and atherosclerosis.T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy.Definition of molecular determinants of prostate cancer cell bone extravasation.In vivo neutralization of α4 and β7 integrins inhibits eosinophil trafficking and prevents lung injury during tropical pulmonary eosinophilia in mice.Impaired P2X1 Receptor-Mediated Adhesion in Eosinophils from Asthmatic Patients.The formation of titan cells in Cryptococcus neoformans depends on the mouse strain and correlates with induction of Th2-type responses.The laminin β1-competing peptide YIGSR induces a hypercontractile, hypoproliferative airway smooth muscle phenotype in an animal model of allergic asthma.Antagonism of cytokine-induced eosinophil accumulation in asthma.Proteomics of Eosinophil Activation.Sialic acid-binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β2-integrin-dependent function in human eosinophils.Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation.
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Roles of integrin activation in eosinophil function and the eosinophilic inflammation of asthma.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Roles of integrin activation i ...... philic inflammation of asthma.
@en
type
label
Roles of integrin activation i ...... philic inflammation of asthma.
@en
prefLabel
Roles of integrin activation i ...... philic inflammation of asthma.
@en
P2093
P2860
P356
P1476
Roles of integrin activation i ...... philic inflammation of asthma.
@en
P2093
Dawn M McNamee
Deane F Mosher
Mats W Johansson
Steven R Barthel
P2860
P356
10.1189/JLB.0607344
P577
2007-10-10T00:00:00Z