Transamidation by transglutaminase 2 transforms S100A11 calgranulin into a procatabolic cytokine for chondrocytes.
about
Tissue transglutaminase is a negative regulator of monomeric lacritin bioactivity.Cellular functions of tissue transglutaminaseGenomic analysis and differential expression of HMG and S100A family in human arthritis: upregulated expression of chemokines, IL-8 and nitric oxide by HMGB1Transglutaminase regulation of cell function.Chondrocyte innate immune myeloid differentiation factor 88-dependent signaling drives procatabolic effects of the endogenous Toll-like receptor 2/Toll-like receptor 4 ligands low molecular weight hyaluronan and high mobility group box chromosomal pS100A11, a dual growth regulator of epidermal keratinocytes.Sumoylation and nuclear translocation of S100A4 regulate IL-1beta-mediated production of matrix metalloproteinase-13.Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammationModels of ex vivo explant cultures: applications in bone researchTransglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA.S100A11: diverse function and pathology corresponding to different target proteins.Human eosinophils express RAGE, produce RAGE ligands, exhibit PKC-delta phosphorylation and enhanced viability in response to the RAGE ligand, S100BPutative multifunctional signature of lung metastases in dedifferentiated chondrosarcoma.S100 proteins in cartilage: role in arthritis.Active Secretion of Dimerized S100A11 Induced by the Peroxisome in Mesothelioma Cells.Changes in chondrocyte gene expression following in vitro impaction of porcine articular cartilage in an impact injury model.Label-free proteomic analysis of the hydrophobic membrane protein complement in articular chondrocytes: a technique for identification of membrane biomarkersFunctions of S100 proteins.RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation.The pattern recognition receptor CD36 is a chondrocyte hypertrophy marker associated with suppression of catabolic responses and promotion of repair responses to inflammatory stimuliCartilage homeostasis in health and rheumatic diseases.RAGE and its ligands in bone metabolism.Homeostatic mechanisms in articular cartilage and role of inflammation in osteoarthritis.Transglutaminase 2 as a biomarker of osteoarthritis: an update.Transglutaminase 2 modulation of NF-κB signaling in astrocytes is independent of its ability to mediate astrocytic viability in ischemic injury.Calgizzarin (S100A11): a novel inflammatory mediator associated with disease activity of rheumatoid arthritisThe danger from within: alarmins in arthritis.Arterial calcification is driven by RAGE in Enpp1-/- mice.RAGE signaling mediates post-injury arterial neointima formation by suppression of liver kinase B1 and AMPK activity.Transglutaminase 2 in cartilage homoeostasis: novel links with inflammatory osteoarthritis.Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α.Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll-like receptor 4.
P2860
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P2860
Transamidation by transglutaminase 2 transforms S100A11 calgranulin into a procatabolic cytokine for chondrocytes.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Transamidation by transglutami ...... lic cytokine for chondrocytes.
@en
type
label
Transamidation by transglutami ...... lic cytokine for chondrocytes.
@en
prefLabel
Transamidation by transglutami ...... lic cytokine for chondrocytes.
@en
P2860
P1476
Transamidation by transglutami ...... lic cytokine for chondrocytes.
@en
P2093
Denise L Cecil
Robert Terkeltaub
P2860
P304
P356
10.4049/JIMMUNOL.180.12.8378
P407
P577
2008-06-01T00:00:00Z