Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α.
about
Cellular ageing mechanisms in osteoarthritisInflammation and intracellular metabolism: new targets in OAEmerging regulators of the inflammatory process in osteoarthritisOsteoarthritis year 2011 in review: biologyReview: Metabolic Regulation of Inflammation in OsteoarthritisAMPK activation--protean potential for boosting healthspan.Shear stress modulates macrophage-induced urokinase plasminogen activator expression in human chondrocytes.MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis.The relationship of autophagy defects to cartilage damage during joint aging in a mouse model.Models of ex vivo explant cultures: applications in bone researchPeroxisome proliferator-activated receptor γ coactivator 1α and FoxO3A mediate chondroprotection by AMP-activated protein kinase.Mitochondrial respiration and redox coupling in articular chondrocytesα-Melanocyte-stimulating-hormone (α-MSH) modulates human chondrocyte activation induced by proinflammatory cytokines.Emerging targets in osteoarthritis therapy.The effects of aging on the development of osteoarthritis.Ageing and the pathogenesis of osteoarthritis.Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury.Mechanotransduction in primary human osteoarthritic chondrocytes is mediated by metabolism of energy, lipids, and amino acids.Deferoxamine Suppresses Collagen Cleavage and Protease, Cytokine, and COL10A1 Expression and Upregulates AMPK and Krebs Cycle Genes in Human Osteoarthritic Cartilage.AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice.Linked decreases in liver kinase B1 and AMP-activated protein kinase activity modulate matrix catabolic responses to biomechanical injury in chondrocytes.Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation.The AMPK enzyme-complex: from the regulation of cellular energy homeostasis to a possible new molecular target in the management of chronic inflammatory disorders.C/EBP homologous protein drives pro-catabolic responses in chondrocytes.Low Shear Stress Attenuates COX-2 Expression Induced by Resistin in Human Osteoarthritic Chondrocytes.Emerging role of metabolic signaling in synovial joint remodeling and osteoarthritis.AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages.Tackling chondrocyte hypertrophy with multifunctional nanoparticles.Suppression of REDD1 in osteoarthritis cartilage, a novel mechanism for dysregulated mTOR signaling and defective autophagyAging and osteoarthritis.Mitochondrial biogenesis is impaired in osteoarthritis chondrocytes but reversible via peroxisome proliferator-activated receptor γ coactivator 1αA vicious circle between insulin resistance and inflammation in nonalcoholic fatty liver disease.Suppression of Sestrins in aging and osteoarthritic cartilage: dysfunction of an important stress defense mechanism.Therapeutic Effects of Olive and Its Derivatives on Osteoarthritis: From Bench to Bedside.Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models.Celastrol attenuates pain and cartilage damage via SDF-1/CXCR4 signalling pathway in osteoarthritis rats.Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice.Proteasomal function is impaired in human osteoarthritic chondrocytes and this can contribute to decreased SOX9 and aggrecan.Regulated in Development and DNA Damage Response 1 Deficiency Impairs Autophagy and Mitochondrial Biogenesis in Articular Cartilage and Increases the Severity of Experimental Osteoarthritis.Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis.
P2860
Q26746549-5A7A4C05-942E-476B-A376-140BF124CF05Q26777620-F7667E6F-0710-463F-817C-8ABCC0FDD861Q26829840-166FE8D4-832E-4796-80A3-AA77B515CCCFQ26853546-27847742-1F25-406A-A8EE-A85DF0C4A11CQ28079875-BF99277A-4090-445C-A2DC-A84C63EE6FC4Q33689169-CE0746CA-E239-4888-8BCA-9BD92B0AF1C5Q33766376-F18D3B16-E79A-42E3-8748-B200CB6F0A6CQ33872848-347A9E0C-5E17-49DE-8EB4-E14A3E1062E4Q34464179-92C500AA-E9B1-4820-9F57-474A1E5D0DE6Q34533989-979AB9D7-5FF3-4A9B-BEA0-51FDD45B220FQ35128583-507E852B-AD9B-4C5F-B442-0CF1D7075D90Q35257654-AC0A6EED-83B2-4C4F-8CFF-79BF8FF14EEFQ35669556-897B73BC-DC48-44AB-BAA9-16A15377773DQ35752078-5D84AFBB-73C4-48D8-B9BA-B345A11B0630Q35809759-0768FCF2-3D99-4C2B-91D0-ED5574156123Q37078239-4C61EBE3-BD36-4FCE-A22A-AA172D9A0E12Q37346907-A1561D8B-5DF5-4EA6-B80C-EDD9F3F83E76Q37397169-6EC919B5-37A9-4CDF-B6ED-DE96D86CEF35Q37500870-421AC1A8-FBDC-4822-B2B6-90A356916ABAQ37657974-412DE3A0-4113-4FF5-8CCA-BFAF3FBAA9D3Q37691067-57AFBEDE-207D-4105-8289-20D44EBE29A5Q38018381-DFB8FFFA-3811-4AA3-AE9D-864183FE1942Q38594411-304BA092-BE02-4023-A070-81A6030EA08EQ38643818-AC86349F-66AF-493D-BED6-627CAE825234Q38741594-A04372D7-B60F-4AC4-B0B0-E5918EC5D9CBQ38948993-90039F7B-003D-4BA3-8960-DD4C1FB13967Q40173526-33A5F82F-1291-4FE7-87A0-271681E07BADQ40716006-E037ACED-4CC2-4597-A816-07E4A7E6BB61Q41484240-519E375C-6BCD-4A3E-ADE1-EED515FA2F68Q42011299-C7538828-C340-4DF5-96C8-E15CDA82CEB4Q42176724-CDAEFCF4-B400-4C41-B519-574C1CB6DA4DQ42379258-DE2B6063-FC87-468B-9B0B-36E71CC32FAFQ42499890-4742397C-DE13-4AC8-816C-A188891326BDQ47101159-CBA4AC8E-B45E-4F5E-83C7-D9F17F480568Q47139731-D34E98B2-C623-47C5-B468-ABFB23A8DDEBQ47673453-F7B4B872-CA9F-4392-8B6B-5B21369E854DQ49121379-64AA0376-B3B4-4182-8760-7C816A7CDC6CQ49860309-5B1B1439-92F7-48FA-B79E-D7DEEF0173B5Q51089710-BCCFA1F1-9471-41AB-926B-676F4E9527C4Q51758259-4F592368-46CC-47D9-9446-01030329A7DC
P2860
Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Chondrocyte AMP-activated prot ...... β and tumor necrosis factor α.
@en
Chondrocyte AMP-activated prot ...... β and tumor necrosis factor α.
@nl
type
label
Chondrocyte AMP-activated prot ...... β and tumor necrosis factor α.
@en
Chondrocyte AMP-activated prot ...... β and tumor necrosis factor α.
@nl
prefLabel
Chondrocyte AMP-activated prot ...... β and tumor necrosis factor α.
@en
Chondrocyte AMP-activated prot ...... β and tumor necrosis factor α.
@nl
P2093
P2860
P356
P1476
Chondrocyte AMP-activated prot ...... β and tumor necrosis factor α.
@en
P2093
Martin Lotz
Robert Terkeltaub
Ru Liu-Bryan
P2860
P304
P356
10.1002/ART.30333
P577
2011-07-01T00:00:00Z