Hematologic disease induced in BALB/c mice by a bcr-abl retrovirus is influenced by the infection conditions.
about
Bcr-Abl with an SH3 deletion retains the ability To induce a myeloproliferative disease in mice, yet c-Abl activated by an SH3 deletion induces only lymphoid malignancyTransformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes.The NH(2)-terminal coiled-coil domain and tyrosine 177 play important roles in induction of a myeloproliferative disease in mice by Bcr-AblModels of chronic myeloid leukemia.Modeling Philadelphia chromosome positive leukemias.The molecular mechanism of chronic myelogenous leukemia and its therapeutic implications: studies in a murine model.Studying the pathogenesis of BCR-ABL+ leukemia in mice.Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice.The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity.BCR-ABL and v-abl oncogenes induce distinct patterns of thymic lymphoma involving different lymphocyte subsets.Novel therapeutic approach to eradicate tyrosine kinase inhibitor resistant chronic myeloid leukemia stem cells.Molecular pathology of tumor-initiating cells: lessons from Philadelphia chromosome-positive leukemia.Philadelphia chromosome-positive acute lymphoblastic leukemia- current concepts and future perspectives.Disease progression in a murine model of bcr/abl leukemogenesis.Animal models of BCR/ABL-induced leukemias.Bcr-Abl has a greater intrinsic capacity than v-Abl to induce the neoplastic expansion of myeloid cells.
P2860
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P2860
Hematologic disease induced in BALB/c mice by a bcr-abl retrovirus is influenced by the infection conditions.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Hematologic disease induced in ...... d by the infection conditions.
@en
type
label
Hematologic disease induced in ...... d by the infection conditions.
@en
prefLabel
Hematologic disease induced in ...... d by the infection conditions.
@en
P2860
P356
P1476
Hematologic disease induced in ...... d by the infection conditions.
@en
P2093
A G Elefanty
P2860
P304
P356
10.1128/MCB.12.4.1755
P407
P50
P577
1992-04-01T00:00:00Z