APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress.
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In vivo processing of ceria nanoparticles inside liver: impact on free-radical scavenging activity and oxidative stressOxidative stress, bone marrow failure, and genome instability in hematopoietic stem cellsBRCA1 and Oxidative StressBase excision repair: a critical player in many gamesATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents.Oxidative stress preferentially induces a subtype of micronuclei and mediates the genomic instability caused by p53 dysfunction.AP endonucleases process 5-methylcytosine excision intermediates during active DNA demethylation in Arabidopsis.Cellular deficiency of Werner syndrome protein or RECQ1 promotes genotoxic potential of hydroquinone and benzo[a]pyrene exposure.Recognition and repair of chemically heterogeneous structures at DNA endsDNA damage: a sensible mediator of the differentiation decision in hematopoietic stem cells and in leukemia.Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylationSlow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative StressAPE2 Zf-GRF facilitates 3'-5' resection of DNA damage following oxidative stress.DNA damage-induced ATM- and Rad-3-related (ATR) kinase activation in non-replicating cells is regulated by the XPB subunit of transcription factor IIH (TFIIH).Cell-free Xenopus egg extracts for studying DNA damage response pathways.Molecular mechanisms of DNA replication checkpoint activationThe accumulation of DNA repair defects is the molecular origin of carcinogenesis.Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress.Importin β-dependent nuclear import of TopBP1 in ATR-Chk1 checkpoint in Xenopus egg extracts.Oxygen atoms are critical in rendering THP-1 leukaemia cells susceptible to cold physical plasma-induced apoptosisATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.Multiple functions of long non-coding RNAs in oxidative stress, DNA damage response and cancer progression.REV1 is important for the ATR-Chk1 DNA damage response pathway in Xenopus egg extracts.Claspin recruits Cdc7 kinase for initiation of DNA replication in human cellsThe DNA repair enzyme apurinic/apyrimidinic endonuclease (Apex nuclease) 2 has the potential to protect against down-regulation of chondrocyte activity in osteoarthritis.Oral ingestion of silver nanoparticles induces genomic instability and DNA damage in multiple tissues.Activation of Checkpoint Kinase Chk1 by Reactive Oxygen Species Resulting from Disruption of wat1/pop3 in Schizosaccharomyces pombe.CiAPEX2 and CiP0, candidates of AP endonucleases in Ciona intestinalis, have 3'-5' exonuclease activity and contribute to protection against oxidative stress.Molecular snapshots of APE1 proofreading mismatches and removing DNA damage.APE2 promotes DNA damage response pathway from a single-strand break.Tumor suppressor Ing1b facilitates DNA repair and prevents oxidative stress induced cell death.Roles of UVA radiation and DNA damage responses in melanoma pathogenesis.Single-Strand Break End Resection in Genome Integrity: Mechanism and Regulation by APE2APURINIC/APYRIMIDINIC ENDONUCLEASE2 and ZINC FINGER DNA 3'-PHOSPHOESTERASE Play Overlapping Roles in the Maintenance of Epigenome and Genome StabilitySelective human inhibitors of ATR and ATM render Leishmania major promastigotes sensitive to oxidative damage
P2860
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P2860
APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress.
@en
type
label
APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress.
@en
prefLabel
APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress.
@en
P2093
P2860
P356
P1476
APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress
@en
P2093
Barry L Lentz
Jeremy Willis
Yogin Patel
P2860
P304
10592-10597
P356
10.1073/PNAS.1301445110
P407
P50
P577
2013-06-10T00:00:00Z