Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.
about
Profile of Aziz Sancar.Cloning of a human homolog of the yeast nucleotide excision repair gene MMS19 and interaction with transcription repair factor TFIIH via the XPB and XPD helicasesDefining the function of xeroderma pigmentosum group F protein in psoralen interstrand cross-link-mediated DNA repair and mutagenesisIsolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIHMapping of interaction domains between human repair proteins ERCC1 and XPFPurification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23Ultraviolet-induced movement of the human DNA repair protein, Xeroderma pigmentosum type G, in the nucleusFormation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteinsReconstitution of human excision nuclease with recombinant XPF-ERCC1 complexCorrection of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair geneA 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcriptionIn vitro repair of oxidative DNA damage by human nucleotide excision repair system: possible explanation for neurodegeneration in xeroderma pigmentosum patientsHuman DNA repair excision nuclease. Analysis of the roles of the subunits involved in dual incisions by using anti-XPG and anti-ERCC1 antibodiesAn alternative form of replication protein a expressed in normal human tissues supports DNA repairA role for the human single-stranded DNA binding protein HSSB/RPA in an early stage of nucleotide excision repairLong-patch DNA repair synthesis during base excision repair in mammalian cellsTFIIH-mediated nucleotide excision repair and initiation of mRNA transcription in an optimized cell-free DNA repair and RNA transcription assayHuman xeroderma pigmentosum group G gene encodes a DNA endonucleaseCorrection of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH)Circadian clock control of the cellular response to DNA damageERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologsThe comings and goings of nucleotide excision repair factors on damaged DNAImpaired nucleotide excision repair upon macrophage differentiation is corrected by E1 ubiquitin-activating enzymeSite-specific incorporation of N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (dG-AAF) into oligonucleotides using modified 'ultra-mild' DNA synthesisRegulation of repair by the 26SproteasomeRepair activity of base and nucleotide excision repair enzymes for guanine lesions induced by nitrosative stress.Global-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo ModifiersXeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulationNucleotide excision repair in eukaryotesTfb5 interacts with Tfb2 and facilitates nucleotide excision repair in yeastRole of the Rad1 and Rad10 proteins in nucleotide excision repair and recombination.Affinity purification and partial characterization of a yeast multiprotein complex for nucleotide excision repair using histidine-tagged Rad14 protein.RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6.DNA repair synthesis during base excision repair in vitro is catalyzed by DNA polymerase epsilon and is influenced by DNA polymerases alpha and delta in Saccharomyces cerevisiae.Yeast Rad7-Rad16 complex, specific for the nucleotide excision repair of the nontranscribed DNA strand, is an ATP-dependent DNA damage sensor.Reconstitution of TFIIH and requirement of its DNA helicase subunits, Rad3 and Rad25, in the incision step of nucleotide excision repair.Reconstitution of yeast nucleotide excision repair with purified Rad proteins, replication protein A, and transcription factor TFIIH.Human transcription release factor 2 dissociates RNA polymerases I and II stalled at a cyclobutane thymine dimerThe general transcription-repair factor TFIIH is recruited to the excision repair complex by the XPA protein independent of the TFIIE transcription factorScreening diagnostic candidates for schistosomiasis from tegument proteins of adult Schistosoma japonicum using an immunoproteomic approach
P2860
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P2860
Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Human nucleotide excision nucl ...... ter bond 3' to the photodimer.
@en
type
label
Human nucleotide excision nucl ...... ter bond 3' to the photodimer.
@en
prefLabel
Human nucleotide excision nucl ...... ter bond 3' to the photodimer.
@en
P2093
P2860
P356
P1476
Human nucleotide excision nucl ...... ter bond 3' to the photodimer.
@en
P2093
D L Svoboda
J T Reardon
P2860
P304
P356
10.1073/PNAS.89.8.3664
P407
P577
1992-04-01T00:00:00Z