Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs.
about
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malariaGametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient dataAntibiotics in malaria therapy: which antibiotics except tetracyclines and macrolides may be used against malaria?New developments in anti-malarial target candidate and product profilesA New Set of Chemical Starting Points with Plasmodium falciparum Transmission-Blocking Potential for Antimalarial Drug DiscoveryCharacterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy ModelingPyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum.An essential role of the basal body protein SAS-6 in Plasmodium male gamete development and malaria transmissionPerforin-like protein PPLP2 permeabilizes the red blood cell membrane during egress of Plasmodium falciparum gametocytesA novel multiple-stage antimalarial agent that inhibits protein synthesisHundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screenDeveloping transmission-blocking strategies for malaria control.Evaluation of Plasmodium falciparum gametocyte detection in different patient material.A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugsEffect of fluorescent dyes on in vitro-differentiated, late-stage Plasmodium falciparum gametocytes.Lead clinical and preclinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations.Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malariaAntimalarial iron chelator FBS0701 blocks transmission by Plasmodium falciparum gametocyte activation inhibition.Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humansSynthesis and evaluation of the antiplasmodial activity of tryptanthrin derivatives.Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation.Nowhere to hide: interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination.Potent Ex Vivo Activity of Naphthoquine and Methylene Blue against Drug-Resistant Clinical Isolates of Plasmodium falciparum and Plasmodium vivax.Plasmodium transmission blocking activities of Vernonia amygdalina extracts and isolated compounds.Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assayA simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compoundsGametocyte Clearance Kinetics Determined by Quantitative Magnetic Fractionation in Melanesian Children with Uncomplicated Malaria Treated with Artemisinin Combination Therapy.A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes.Luciferase-Based, High-Throughput Assay for Screening and Profiling Transmission-Blocking Compounds against Plasmodium falciparum Gametocytes.Single low dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission after artemether-lumefantrine in children with asymptomatic infection: a randomised, double-blind, placebo-controlled trial.Inclusion of gametocyte parameters in anti-malarial drug efficacy studies: filling a neglected gap needed for malaria eliminationIn Vitro Activities of Primaquine-Schizonticide Combinations on Asexual Blood Stages and Gametocytes of Plasmodium falciparumThe Nonartemisinin Sesquiterpene Lactones Parthenin and Parthenolide Block Plasmodium falciparum Sexual Stage Transmission.Transmission-Blocking Potential of MEFAS, a Hybrid Compound Derived from Artesunate and MefloquinePiperaquine Monotherapy of Drug-Susceptible Plasmodium falciparum Infection Results in Rapid Clearance of Parasitemia but Is Followed by the Appearance of Gametocytemia.A novel validated assay to support the discovery of new anti-malarial gametocytocidal agents.Malaria parasite clearance.New insight-guided approaches to detect, cure, prevent and eliminate malaria.Use of quantitative pharmacology tools to improve malaria treatments.Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.
P2860
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P2860
Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Male and female Plasmodium fal ...... sponses to antimalarial drugs.
@en
type
label
Male and female Plasmodium fal ...... sponses to antimalarial drugs.
@en
prefLabel
Male and female Plasmodium fal ...... sponses to antimalarial drugs.
@en
P2093
P2860
P356
P1476
Male and female Plasmodium fal ...... sponses to antimalarial drugs.
@en
P2093
Esperanza Herreros
Jöel Lelièvre
María José López-Barragán
Robert E Sinden
Sara Marques
Ursula Straschil
P2860
P304
P356
10.1128/AAC.00325-13
P407
P577
2013-04-29T00:00:00Z