Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis.
about
Actin cytoskeletal defects in immunodeficiencyWIP regulates persistence of cell migration and ruffle formation in both mesenchymal and amoeboid modes of motilityDOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memoryWiskott-Aldrich syndrome protein (WASP) and N-WASP are critical for peripheral B-cell development and functionA balance of Bruton's tyrosine kinase and SHIP activation regulates B cell receptor cluster formation by controlling actin remodeling.The tumor promoter and NF-κB modulator Bcl-3 regulates splenic B cell development.Hematopoietic cell transplantation for Wiskott-Aldrich syndrome: advances in biology and future directions for treatment.Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative studyFoamy virus vector-mediated gene correction of a mouse model of Wiskott-Aldrich syndrome.Wiskott-Aldrich syndrome protein is required for homeostasis and function of invariant NKT cells.How B cells capture, process and present antigens: a crucial role for cell polarity.Exacerbated experimental arthritis in Wiskott-Aldrich syndrome protein deficiency: modulatory role of regulatory B cellsN-wasp is essential for the negative regulation of B cell receptor signaling.Defective inhibition of B-cell proliferation by Wiskott-Aldrich syndrome protein-deficient regulatory T cellsWASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity.The Rho GTPase Cdc42 Is Essential for the Activation and Function of Mature B Cells.B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice.Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome.Dendritic cell functional improvement in a preclinical model of lentiviral-mediated gene therapy for Wiskott-Aldrich syndromeAutoimmunity in wiskott-Aldrich syndrome: an unsolved enigma.B-cell intrinsic TLR7 signals promote depletion of the marginal zone in a murine model of Wiskott-Aldrich syndrome.Wiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells.Wiskott-Aldrich Syndrome at the nexus of autoimmune and primary immunodeficiency diseases.Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiencyWiskott-Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activationSignal Integration during T Lymphocyte Activation and Function: Lessons from the Wiskott-Aldrich Syndrome.B cell subsets are modulated during allergic airway inflammation but are not required for the development of respiratory tolerance in a murine model.A Chemoattractant-Guided Walk Through Lymphopoiesis: From Hematopoietic Stem Cells to Mature B Lymphocytes.Cytoskeletal control of B cell responses to antigens.Validation of a mutated PRE sequence allowing high and sustained transgene expression while abrogating WHV-X protein synthesis: application to the gene therapy of WAS.Spontaneous germinal centers and autoimmunity.The early activation of memory B cells from Wiskott-Aldrich syndrome patients is suppressed by CD19 downregulation.Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult.Autonomous role of Wiskott-Aldrich Syndrome platelet deficiency in inducing autoimmunity and inflammation.Distinct Roles for Bruton's Tyrosine Kinase in B Cell Immune Synapse Formation
P2860
Q27021852-9A57906D-4490-4485-8635-E6F3118A27F3Q27310306-BF109ACA-974F-4F18-B9E0-319BC421589FQ28506290-58D04A1E-812D-4F52-9C25-DF1FF761BD5EQ28512842-35F15037-66CE-464E-A031-001B29D3CE6DQ30501434-C2D98CB7-D1B3-4110-A59B-F37700C5A9B5Q30560173-53EBA196-256B-45AB-9B16-360388752E7BQ33389727-1FC577B8-C679-4D7E-860D-65D22540E94FQ33395718-AFA90B74-A422-4A0A-B0D7-FB5DA472892AQ33399020-BCD57141-C51A-4102-8776-7BA38169C7F3Q33698035-1165FF38-735B-4636-A936-D6E8A3755621Q34353214-F162FCD1-183B-43C7-BFBD-2A08319F21A6Q34406496-DF5303BF-C7EB-4EA2-A79E-D3D011714C5AQ35040533-A7E11079-94AE-49EA-AD28-F29E2FA27325Q35067630-A86F24FB-E114-4105-9C55-E3E038A6A38AQ35237494-D396EAFC-B63B-425A-8C99-3A4F9367593AQ35560702-717928B1-0500-406F-8DFB-89798EA21D1CQ35891625-EBE858A6-F5D1-4509-82DC-59050C71748BQ35995198-8D479F3F-BF3B-4A21-B55A-178212C21469Q36043410-492EC786-77AF-4AA8-8093-E5F7F75BC75DQ36101320-720A4F81-5800-4FCB-AED7-9048486A7ADFQ36371940-962157DE-1533-4D1B-8313-A659CA9F0D20Q36603542-9920AFB1-E727-4047-9473-05BF9717012EQ36632359-CA549859-DA31-4928-B7F7-DAF293B8E46CQ37132013-658042AC-1771-4F0B-9809-187371EC3E06Q37560331-74CEE4D1-BA4F-45C9-8323-A8C12576BE66Q38364694-D9FF4BA0-6053-4CD0-A213-9C5A755E385AQ39084773-B65024A2-C586-451A-8498-552B9E2755B7Q39245050-92D28C8B-4E99-4EA7-AB60-8ED0E65C92BDQ39424290-298B74D0-955F-4A54-8E68-832D9510FB3BQ39877036-D440DA73-9423-4D88-9A61-FF60BFC4FFD7Q40343247-3ED33CA3-1C99-4235-9428-47E576B813FEQ41663764-C776946A-4539-4855-BA63-AE6812553B32Q45869832-755B38BB-67B0-4E5D-91C3-840FEFF48F5FQ50111884-F213918E-0EB7-48C0-97D8-932C9C96D922Q58761365-7A60D779-BD2B-4F10-982E-B28883C3D44F
P2860
Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Wiskott-Aldrich syndrome prote ...... paired peripheral homeostasis.
@en
type
label
Wiskott-Aldrich syndrome prote ...... paired peripheral homeostasis.
@en
prefLabel
Wiskott-Aldrich syndrome prote ...... paired peripheral homeostasis.
@en
P2093
P2860
P50
P1433
P1476
Wiskott-Aldrich syndrome prote ...... paired peripheral homeostasis.
@en
P2093
Almut Meyer-Bahlburg
David J Rawlings
Facundo D Batista
Shirly Becker-Herman
Socheath Khim
Stephanie Humblet-Baron
P2860
P304
P356
10.1182/BLOOD-2008-02-140814
P407
P577
2008-08-07T00:00:00Z