p16INK4a-induced senescence is disabled by melanoma-associated mutations
about
A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cellsThe chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4aGeneration of a genome scale lentiviral vector library for EF1α promoter-driven expression of human ORFs and identification of human genes affecting viral titerWnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells.The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence.The p16(INK4A) tumor suppressor regulates cellular oxidative stressmiRNA-205 suppresses melanoma cell proliferation and induces senescence via regulation of E2F1 protein.The evolving role of radiation therapy in the management of malignant melanomaFuture of radiation therapy for malignant melanoma in an era of newer, more effective biological agents.Advances in melanoma senescence and potential clinical application.DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.Senescence-Like Phenotypes in Human Nevi.CDKN2A unclassified variants in familial malignant melanoma: combining functional and computational approaches for their assessment.The Strange Case of CDK4/6 Inhibitors: Mechanisms, Resistance, and Combination Strategies.Glucose metabolite glyoxal induces senescence in telomerase-immortalized human mesenchymal stem cellsMalignancy without immortality? Cellular immortalization as a possible late event in melanoma progression.Pathways from senescence to melanoma: focus on MITF sumoylation.The Role of Sumoylation in Senescence.Molecular pathology of cutaneous melanoma
P2860
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P2860
p16INK4a-induced senescence is disabled by melanoma-associated mutations
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
p16INK4a-induced senescence is disabled by melanoma-associated mutations
@en
type
label
p16INK4a-induced senescence is disabled by melanoma-associated mutations
@en
prefLabel
p16INK4a-induced senescence is disabled by melanoma-associated mutations
@en
P2860
P50
P1433
P1476
p16INK4a-induced senescence is disabled by melanoma-associated mutations
@en
P2093
Lyndee L Scurr
Sebastian Haferkamp
P2860
P304
P356
10.1111/J.1474-9726.2008.00422.X
P577
2008-10-01T00:00:00Z