Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans.
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Induction of human beta-cell proliferation and engraftment using a single G1/S regulatory molecule, cdk6RETRACTED: Betatrophin: a hormone that controls pancreatic β cell proliferationBeneficial endocrine but adverse exocrine effects of sitagliptin in the human islet amyloid polypeptide transgenic rat model of type 2 diabetes: interactions with metforminβ-cell replacement sources for type 1 diabetes: a focus on pancreatic ductal cellsDynamic pathology of islet endocrine cells in type 2 diabetes: β-Cell growth, death, regeneration and their clinical implicationsReport from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell ReplacementMaternal microchimerism: friend or foe in type 1 diabetes?Role of microRNAs in islet beta-cell compensation and failure during diabetesConcise review: pancreas regeneration: recent advances and perspectivesMaintenance of β-cell maturity and plasticity in the adult pancreas: developmental biology concepts in adult physiologyIL-2 immunotherapy reveals potential for innate beta cell regeneration in the non-obese diabetic mouse model of autoimmune diabetesβ-cell dysfunction: Its critical role in prevention and management of type 2 diabetes.The Rise and the Fall of Betatrophin/ANGPTL8 as an Inducer of β-Cell ProliferationNatural history of β-cell adaptation and failure in type 2 diabetesInsulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitroEpoxypukalide induces proliferation and protects against cytokine-mediated apoptosis in primary cultures of pancreatic β-cellsDifferential and complementary effects of glucose and prolactin on islet DNA synthesis and gene expressionIn vitro proliferation of adult human beta-cellsPancreatic islet plasticity: interspecies comparison of islet architecture and compositionMetabolism Disrupting Chemicals and Metabolic DisordersIslet biology, the CDKN2A/B locus and type 2 diabetes risk.Adult tissue sources for new β cells.Dynamics of beta-cell turnover: evidence for beta-cell turnover and regeneration from sources of beta-cells other than beta-cell replication in the HIP ratAdaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy.Cytoplasmic-nuclear trafficking of G1/S cell cycle molecules and adult human β-cell replication: a revised model of human β-cell G1/S controlIs dynamic autocrine insulin signaling possible? A mathematical model predicts picomolar concentrations of extracellular monomeric insulin within human pancreatic islets.ALDH expression characterizes G1-phase proliferating beta cells during pregnancy.β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.Pancreatic β-cell proliferation in obesity.Recurrence of autoimmunity following pancreas transplantation.Age-associated changes of islet endocrine cells and the effects of body mass index in Japanese.Slow and steady is the key to beta-cell replication.EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.Development of factors to convert frequency to rate for beta-cell replication and apoptosis quantified by time-lapse video microscopy and immunohistochemistry.The negative cell cycle regulators, p27(Kip1), p18(Ink4c), and GSK-3, play critical role in maintaining quiescence of adult human pancreatic β-cells and restrict their ability to proliferate.Current status of islet cell replacement and regeneration therapy.Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodentsInsulin secretion and insulin-producing tumorsNeuropeptide Y expression marks partially differentiated β cells in mice and humansBeta-cell replication is increased in donor organs from young patients after prolonged life support.
P2860
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P2860
Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Beta-cell replication is the p ...... n of beta-cell mass in humans.
@en
type
label
Beta-cell replication is the p ...... n of beta-cell mass in humans.
@en
prefLabel
Beta-cell replication is the p ...... n of beta-cell mass in humans.
@en
P2093
P2860
P356
P1433
P1476
Beta-cell replication is the p ...... n of beta-cell mass in humans.
@en
P2093
Alexandra E Butler
Anil Bhushan
Juris J Meier
Peter C Butler
Robert A Rizza
Ryan Galasso
Travis Monchamp
Yoshifumi Saisho
P2860
P304
P356
10.2337/DB07-1369
P407
P577
2008-03-11T00:00:00Z