RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α - Wikidata - wikimedia - TriplyDB

RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α

RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α

http://www.wikidata.org/entity/Q36971996

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Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA Examining the pathogenesis of breast cancer using a novel agent-based model of mammary ductal epithelium dynamics An early biomarker and potential therapeutic target of RUNX 3 hypermethylation in breast cancer, a system review and meta-analysis Associations between genetic variants in the TGF-β signaling pathway and breast cancer risk among Hispanic and non-Hispanic white women.Identification of differentially methylated genes in the malignant transformation of ovarian endometriosis.Genome-wide screening of genes regulated by DNA methylation in colon cancer development.Clinicopathological significance and potential drug target of RUNX3 in breast cancer.Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells.Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness Tumor suppressor function of RUNX3 in breast cancer Prolyl isomerase Pin1 downregulates tumor suppressor RUNX3 in breast cancer.RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer.TrkB Promotes Breast Cancer Metastasis via Suppression of Runx3 and Keap1 Expression The clinicopathological significance of RUNX3 hypermethylation and mRNA expression in human breast cancer, a meta-analysis.Dysregulation of Notch and ERα signaling in AhR-/- male mice.Candidate luminal B breast cancer genes identified by genome, gene expression and DNA methylation profiling The RUNX family in breast cancer: relationships with estrogen signaling.RUNX family: Regulation and diversification of roles through interacting proteins.The RUNX family: developmental regulators in cancer.Hormone-sensing mammary epithelial progenitors: emerging identity and hormonal regulation.Relationship between RUNX1 and AXIN1 in ER-negative versus ER-positive Breast Cancer.The enigmatic role of RUNX1 in female-related cancers - current knowledge & future perspectives.Runx3 in Immunity, Inflammation and Cancer.RUNX3 is a prognostic marker and potential therapeutic target in human breast cancer.RUNX3 interacts with MYCN and facilitates protein degradation in neuroblastoma.MicroRNA-148a can regulate runt-related transcription factor 3 gene expression via modulation of DNA methyltransferase 1 in gastric cancer Runx Genes in Breast Cancer and the Mammary Lineage.Expression and methylation patterns partition luminal-A breast tumors into distinct prognostic subgroups.RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer.miR-130a acts as a potential diagnostic biomarker and promotes gastric cancer migration, invasion and proliferation by targeting RUNX3.Transcriptional regulation by RUNX3 Epigenome-wide association studies without the need for cell-type composition.Combination immunohistochemistry for SMAD4 and Runt-related transcription factor 3 may identify a favorable prognostic subgroup of pancreatic ductal adenocarcinomas.EZH2 promotes cell proliferation by regulating the expression of RUNX3 in laryngeal carcinoma.Roles of RUNX in Solid Tumors.A Regulatory Role for RUNX1, RUNX3 in the Maintenance of Genomic Integrity.Runx3 and Cell Fate Decisions in Pancreas Cancer.Shugan Liangxue Decoction () down-regulates estrogen receptor α expression in breast cancer cells.Susceptibility loci affecting ERBB2/neu-induced mammary tumorigenesis in mice.

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P2860

RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α

http://www.wikidata.org/entity/Q36971996

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RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α

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RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α

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RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α

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RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α

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B Huang

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C W Ong

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D Shapiro

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G Xiao

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K Ito

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L-F Chen

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M Salto-Tellez

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Y Ito

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Y-H N Tsang

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Z Qu

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P2860

RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis

The role of oestrogen and progesterone receptors in human mammary development and tumorigenesis

Estrogen receptor transcription and transactivation: Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer.

The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation.

RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD.

Estrogen regulation of mammary gland development and breast cancer: amphiregulin takes center stage

The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis.

Abnormal regulation of the oestrogen receptor in benign breast lesions.

Oncogenic potential of the RUNX gene family: 'overview'.

Signaling by estrogens.

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10.1038/ONC.2011.252

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