about
The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend.Platelet aggregation responses are critically regulated in vivo by endogenous nitric oxide but not by endothelial nitric oxide synthaseThrombin and collagen induce a feedback inhibitory signaling pathway in platelets involving dissociation of the catalytic subunit of protein kinase A from an NFkappaB-IkappaB complex.The anti-aggregating effect of BAY 41-2272, a stimulator of soluble guanylyl cyclase, requires the presence of nitric oxide.Platelet hemostasis in patients with metabolic syndrome and type 2 diabetes mellitus: cGMP- and NO-dependent mechanisms in the insulin-mediated platelet aggregation.Abnormal platelet aggregation in idiopathic pulmonary arterial hypertension: role of nitric oxide.Nitric oxide at a glance.Critical role for oxidative stress, platelets, and coagulation in capillary blood flow impairment in sepsis.Nitric oxide regulates multiple functions and fate of adult progenitor and stem cells.A review and discussion of platelet nitric oxide and nitric oxide synthase: do blood platelets produce nitric oxide from L-arginine or nitrite?Serum nitric oxide levels in patients with Crimean-Congo haemorrhagic fever.Insulin, insulin resistance, and platelet signaling in diabetes.Nitric oxide inhibits platelet adhesion to collagen through cGMP-dependent and independent mechanisms: the potential role for S-nitrosylation.Elevated plasma concentration of NO and cGMP may be responsible for the decreased platelet aggregation and platelet leukocyte conjugation in platelets hypo-responsive to catecholamines.Nitric oxide inhibits von Willebrand factor-mediated platelet adhesion and spreading through regulation of integrin alpha(IIb)beta(3) and myosin light chain.NO-synthase-/NO-independent regulation of human and murine platelet soluble guanylyl cyclase activity.Role of inorganic nitrate and nitrite in driving nitric oxide-cGMP-mediated inhibition of platelet aggregation in vitro and in vivo.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Unresolved roles of platelet nitric oxide synthase.
@en
type
label
Unresolved roles of platelet nitric oxide synthase.
@en
prefLabel
Unresolved roles of platelet nitric oxide synthase.
@en
P2860
P1476
Unresolved roles of platelet nitric oxide synthase.
@en
P2093
P2860
P356
10.1111/J.1538-7836.2007.02802.X
P577
2007-10-15T00:00:00Z