Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis.
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityInterferon regulatory factor 1 transactivates expression of human DNA polymerase η in response to carcinogen N-methyl-N'-nitro-N-nitrosoguanidineRole of PCNA-dependent stimulation of 3'-phosphodiesterase and 3'-5' exonuclease activities of human Ape2 in repair of oxidative DNA damageSeparate roles of structured and unstructured regions of Y-family DNA polymerasesStructure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchangeStructural Basis of Ubiquitin Recognition by Translesion Synthesis DNA Polymerase ιIdentification of Small Molecule Proliferating Cell Nuclear Antigen (PCNA) Inhibitor That Disrupts Interactions with PIP-box Proteins and Inhibits DNA ReplicationPCNA monoubiquitylation and DNA polymerase eta ubiquitin-binding domain are required to prevent 8-oxoguanine-induced mutagenesis in Saccharomyces cerevisiae.Elg1, an alternative subunit of the RFC clamp loader, preferentially interacts with SUMOylated PCNA.The Proliferating Cell Nuclear Antigen (PCNA)-interacting Protein (PIP) Motif of DNA Polymerase η Mediates Its Interaction with the C-terminal Domain of Rev1Role of PCNA and TLS polymerases in D-loop extension during homologous recombination in humansProcessivity factor of DNA polymerase and its expanding role in normal and translesion DNA synthesisIdentification of two functional PCNA-binding domains in human DNA polymerase κDNA polymerase eta lacking the ubiquitin-binding domain promotes replicative lesion bypass in humans cells.PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells.Replication Past the γ-Radiation-Induced Guanine-Thymine Cross-Link G[8,5-Me]T by Human and Yeast DNA Polymerase ηATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage.Role of the ubiquitin-binding domain of Polη in Rad18-independent translesion DNA synthesis in human cell extracts.The unusual UBZ domain of Saccharomyces cerevisiae polymerase ηPhosphorylated Rad18 directs DNA polymerase η to sites of stalled replicationHyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liverTumour suppressor ING1b maintains genomic stability upon replication stress.Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplicationDNA polymerase η is regulated by poly(rC)-binding protein 1 via mRNA stabilityReversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells.The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis.DNA-damage tolerance mediated by PCNA*Ub fusions in human cells is dependent on Rev1 but not Polη.Role of DNA damage-induced replication checkpoint in promoting lesion bypass by translesion synthesis in yeast.PCNA tool belts and polymerase bridges form during translesion synthesisFunctional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif.Mechanisms of Post-Replication DNA RepairDNA polymerase eta and chemotherapeutic agents.Roles of sequential ubiquitination of PCNA in DNA-damage tolerance.Translesion DNA synthesis in the context of cancer research.Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.Regulation of human DNA polymerase delta in the cellular responses to DNA damage.REV1 and DNA polymerase zeta in DNA interstrand crosslink repair.Readers of PCNA modificationsOxidative Modification and Its Implications for the Neurodegeneration of Parkinson's Disease.Different types of interaction between PCNA and PIP boxes contribute to distinct cellular functions of Y-family DNA polymerases.
P2860
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P2860
Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Roles of PCNA-binding and ubiq ...... in translesion DNA synthesis.
@en
type
label
Roles of PCNA-binding and ubiq ...... in translesion DNA synthesis.
@en
prefLabel
Roles of PCNA-binding and ubiq ...... in translesion DNA synthesis.
@en
P2093
P2860
P356
P1476
Roles of PCNA-binding and ubiq ...... in translesion DNA synthesis.
@en
P2093
Himabindu Gali
Ildiko Unk
Jerard Hurwitz
Jung-Hoon Yoon
Lajos Haracska
Louise Prakash
Narottam Acharya
Robert E Johnson
Satya Prakash
P2860
P304
17724-17729
P356
10.1073/PNAS.0809844105
P407
P577
2008-11-10T00:00:00Z