A novel function of adenomatous polyposis coli (APC) in regulating DNA repair.
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The Ran Pathway in Drosophila melanogaster MitosisDNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancerA knock-in mouse model reveals roles for nuclear Apc in cell proliferation, Wnt signal inhibition and tumor suppression.Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.Interacting partners of FEN1 and its role in the development of anticancer therapeutics.Folate deficiency provides protection against colon carcinogenesis in DNA polymerase beta haploinsufficient miceNuclear adenomatous polyposis coli suppresses colitis-associated tumorigenesis in mice.Genome-wide profiling of pluripotent cells reveals a unique molecular signature of human embryonic germ cells.Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesisAdenomatous polyposis coli interacts with flap endonuclease 1 to block its nuclear entry and functionMolecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis.Correlation between mutations and mRNA expression of APC and MUTYH genes: new insight into hereditary colorectal polyposis predisposition.Molecular biology of gynecological cancer.Adenomatous polyposis coli-mediated accumulation of abasic DNA lesions lead to cigarette smoke condensate-induced neoplastic transformation of normal breast epithelial cells.More than two decades of Apc modeling in rodentsInteraction between APC and Fen1 during breast carcinogenesis.A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC.A novel inhibitor of DNA polymerase beta enhances the ability of temozolomide to impair the growth of colon cancer cells.Targeting DNA polymerase ß for therapeutic intervention.APC as a mobile scaffold: regulation and function at the nucleus, centrosomes, and mitochondria.Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs.Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer.Assembly of the base excision repair complex on abasic DNA and role of adenomatous polyposis coli on its functional activity.Molecular Characterization of Somatic Alterations in Dukes' B and C Colorectal Cancers by Targeted SequencingUbiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway.Clinical and genetic characterization of classical forms of familial adenomatous polyposis: a Spanish population study.
P2860
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P2860
A novel function of adenomatous polyposis coli (APC) in regulating DNA repair.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A novel function of adenomatous polyposis coli (APC) in regulating DNA repair.
@en
type
label
A novel function of adenomatous polyposis coli (APC) in regulating DNA repair.
@en
prefLabel
A novel function of adenomatous polyposis coli (APC) in regulating DNA repair.
@en
P2860
P1433
P1476
A novel function of adenomatous polyposis coli (APC) in regulating DNA repair.
@en
P2093
Aruna S Jaiswal
Satya Narayan
P2860
P304
P356
10.1016/J.CANLET.2008.06.024
P407
P577
2008-07-26T00:00:00Z