Zinc chelation induces rapid depletion of the X-linked inhibitor of apoptosis and sensitizes prostate cancer cells to TRAIL-mediated apoptosis.
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Zinc and zinc transporters in prostate carcinogenesisZinc coordination is required for and regulates transcription activation by Epstein-Barr nuclear antigen 1Copper chelation selectively kills colon cancer cells through redox cycling and generation of reactive oxygen speciesZinc proteome interaction network as a model to identify nutrient-affected pathways in human pathologiesCadmium down-regulates expression of XIAP at the post-transcriptional level in prostate cancer cells through an NF-kappaB-independent, proteasome-mediated mechanism.Essential role of p53 in TPEN-induced neuronal apoptosis.Poly(ADP-ribosyl)ation of p53 contributes to TPEN-induced neuronal apoptosis.On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics.Derivatives of Procaspase-Activating Compound 1 (PAC-1) and their Anticancer Activities.Characterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells: ROLES IN REGULATING CYTOSOLIC ZINC HOMEOSTASIS AND INSULIN SECRETION.Targeting procaspase-3 with WF-208, a novel PAC-1 derivative, causes selective cancer cell apoptosisNovel Polypyridyl chelators deplete cellular zinc and destabilize the X-linked inhibitor of apoptosis protein (XIAP) prior to induction of apoptosis in human prostate and breast cancer cells.Piperlongumine induces rapid depletion of the androgen receptor in human prostate cancer cellsThe effect of 5-aminolevulinic acid and its derivatives on protoporphyrin IX accumulation and apoptotic cell death in castrate-resistant prostate cancer cellsTPEN induces apoptosis independently of zinc chelator activity in a model of acute lymphoblastic leukemia and ex vivo acute leukemia cells through oxidative stress and mitochondria caspase-3- and AIF-dependent pathways.Chelators for investigating zinc metalloneurochemistry.Prostate-specific membrane antigen-targeted liposomes specifically deliver the Zn(2+) chelator TPEN inducing oxidative stress in prostate cancer cells.Tris(2-pyridylmethyl)amine (TPA) as a membrane-permeable chelator for interception of biological mobile zinc.Zinc-rich inhibitor of apoptosis proteins (IAPs) as regulatory factors in the epithelium of normal and inflamed airways.Amino Acid Profiling of Zinc Resistant Prostate Cancer Cell Lines: Associations With Cancer Progression.A novel small-molecule activator of procaspase-3 induces apoptosis in cancer cells and reduces tumor growth in human breast, liver and gallbladder cancer xenografts.Clioquinol induces cytoplasmic clearance of the X-linked inhibitor of apoptosis protein (XIAP): therapeutic indication for prostate cancer.Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway.Influence of zinc and zinc chelator on HT-29 colorectal cell line.Zinc depletion regulates the processing and secretion of IL-1β.Zinc depletion promotes apoptosis-like death in drug-sensitive and antimony-resistance Leishmania donovaniThe cytotoxic and pro-apoptotic activities of the novel fluoropyrimidine F10 towards prostate cancer cells are enhanced by Zn(2+) -chelation and inhibiting the serine protease Omi/HtrA2.Proteomic profiling reveals that collismycin A is an iron chelator.(Acetonitrile){2-[bis-(pyridin-2-ylmethyl-κ(2)N)amino-κN]-N-(2,6-dimethyl-phen-yl)acetamide-κO}(perchlorato-κO)zinc (acetonitrile){2-[bis-(pyridin-2-ylmethyl-κ(2)N)amino-κN]-N-(2,6-dimethyl-phen-yl)acetamide-κO}zinc tris-(perchlorate).Metal chelator TPEN selectively induces apoptosis in K562 cells through reactive oxygen species signaling mechanism: implications for chronic myeloid leukemia.The convergent roles of NF-κB and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma.
P2860
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P2860
Zinc chelation induces rapid depletion of the X-linked inhibitor of apoptosis and sensitizes prostate cancer cells to TRAIL-mediated apoptosis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Zinc chelation induces rapid d ...... s to TRAIL-mediated apoptosis.
@en
type
label
Zinc chelation induces rapid d ...... s to TRAIL-mediated apoptosis.
@en
prefLabel
Zinc chelation induces rapid d ...... s to TRAIL-mediated apoptosis.
@en
P2093
P2860
P356
P1476
Zinc chelation induces rapid d ...... s to TRAIL-mediated apoptosis.
@en
P2093
K Golovine
P L Crispen
V M Kolenko
P2860
P2888
P304
P356
10.1038/CDD.2008.106
P577
2008-07-11T00:00:00Z