A novel small-molecule activator of procaspase-3 induces apoptosis in cancer cells and reduces tumor growth in human breast, liver and gallbladder cancer xenografts.
about
Small-Molecule Procaspase-3 Activation Sensitizes Cancer to Treatment with Diverse ChemotherapeuticsExpression of executioner procaspases and their activation by a procaspase-activating compound in chronic lymphocytic leukemia cellsRemoval of Metabolic Liabilities Enables Development of Derivatives of Procaspase-Activating Compound 1 (PAC-1) with Improved PharmacokineticsDerivatives of Procaspase-Activating Compound 1 (PAC-1) and their Anticancer Activities.Targeting procaspase-3 with WF-208, a novel PAC-1 derivative, causes selective cancer cell apoptosisSM-1, a novel PAC-1 derivative, activates procaspase-3 and causes cancer cell apoptosis.The Combination of Vemurafenib and Procaspase-3 Activation Is Synergistic in Mutant BRAF Melanomas.Synergistic and targeted therapy with a procaspase-3 activator and temozolomide extends survival in glioma rodent models and is feasible for the treatment of canine malignant glioma patients.Multiple mechanisms of zinc-mediated inhibition for the apoptotic caspases -3, -6, -7, & -8.Antioxidant acetophenone glycosides from the roots of Euphorbia ebracteolata Hayata.
P2860
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P2860
A novel small-molecule activator of procaspase-3 induces apoptosis in cancer cells and reduces tumor growth in human breast, liver and gallbladder cancer xenografts.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
A novel small-molecule activat ...... gallbladder cancer xenografts.
@en
type
label
A novel small-molecule activat ...... gallbladder cancer xenografts.
@en
prefLabel
A novel small-molecule activat ...... gallbladder cancer xenografts.
@en
P2093
P2860
P1433
P1476
A novel small-molecule activat ...... gallbladder cancer xenografts.
@en
P2093
Fangyang Wang
Guanfang Ping
Jingyu Yang
Lihui Wang
Yanfang Zhao
P2860
P304
P356
10.1016/J.MOLONC.2014.06.015
P577
2014-07-03T00:00:00Z