The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation.
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Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and diseaseProtein phosphatases and Alzheimer's diseaseRole of Striatal-Enriched Tyrosine Phosphatase in Neuronal FunctionAmyloid-β-Induced Dysregulation of AMPA Receptor TraffickingEmerging Link between Alzheimer's Disease and Homeostatic Synaptic PlasticityCellular biochemistry methods for investigating protein tyrosine phosphatasesThe pathophysiology of fragile X (and what it teaches us about synapses)Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromesInhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice.Striatal-enriched protein tyrosine phosphatase in Alzheimer's disease.Metabotropic glutamate receptor dependent long-term depression in the cortexStriatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicitySTEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's diseaseGenetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model.Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse modelThe tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medicationsAlcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase.Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's diseaseChecking the STEP-Associated Trafficking and Internalization of Glutamate Receptors for Reduced Cognitive Deficits: A Machine Learning Approach-Based Cheminformatics Study and Its Application for Drug RepurposingExtrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEPA substrate trapping mutant form of striatal-enriched protein tyrosine phosphatase prevents amphetamine-induced stereotypies and long-term potentiation in the striatumCellular distribution of AMPA receptor subunits and mGlu5 following acute and repeated administration of morphine or methamphetaminePhosphorylation of FMRP and alterations of FMRP complex underlie enhanced mLTD in adult rats triggered by early life seizures.From FMRP function to potential therapies for fragile X syndrome.Metabotropic glutamate receptors: from the workbench to the bedside.The Role of Proteases in Hippocampal Synaptic Plasticity: Putting Together Small Pieces of a Complex Puzzle.Computational identification of potential multitarget treatments for ameliorating the adverse effects of amyloid-β on synaptic plasticityNecessary, but not sufficient: insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizuresDysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismReduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalizationTherapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders.Protein tyrosine phosphatases as potential therapeutic targets.Increasing our understanding of human cognition through the study of Fragile X Syndrome.Disruption of striatal-enriched protein tyrosine phosphatase (STEP) function in neuropsychiatric disordersHomeostatic scaling requires group I mGluR activation mediated by Homer1a.Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathwaySTEP regulation of seizure thresholds in the hippocampus.Oxidative stress-induced oligomerization inhibits the activity of the non-receptor tyrosine phosphatase STEP61.Protein tyrosine phosphatase receptor type R is required for Purkinje cell responsiveness in cerebellar long-term depression
P2860
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P2860
The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The tyrosine phosphatase STEP ...... lutamate receptor stimulation.
@en
type
label
The tyrosine phosphatase STEP ...... lutamate receptor stimulation.
@en
prefLabel
The tyrosine phosphatase STEP ...... lutamate receptor stimulation.
@en
P2093
P2860
P1476
The tyrosine phosphatase STEP ...... glutamate receptor stimulation
@en
P2093
Clare M Gladding
Deepa V Venkitaramani
Graham L Collingridge
Paul J Lombroso
Pradeep Kurup
Yang Zhang
Yongfang Zhang
P2860
P304
10561-10566
P356
10.1523/JNEUROSCI.2666-08.2008
P407
P50
P577
2008-10-01T00:00:00Z