Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization
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Protein phosphatases and Alzheimer's diseaseAmyloid-β-Induced Dysregulation of AMPA Receptor TraffickingStriatal-enriched protein tyrosine phosphatase in Alzheimer's disease.STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's diseaseSubstrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase.Disruption of striatal-enriched protein tyrosine phosphatase (STEP) function in neuropsychiatric disordersLife extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice.Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathwayStriatal-enriched protein tyrosine phosphatase controls responses to aversive stimuli: implication for ethanol drinking.Synthesis of benzopentathiepin analogs and their evaluation as inhibitors of the phosphatase STEP.Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's diseaseGluA2 AMPA glutamate receptor subunit exhibits codon 607 Q/R RNA editing in the lens.Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity.Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels.Seizure-Induced Regulations of Amyloid-β, STEP61, and STEP61 Substrates Involved in Hippocampal Synaptic Plasticity.The tyrosine phosphatase STEP constrains amygdala-dependent memory formation and neuroplasticity.Involvement of PTPN5, the gene encoding the striatal-enriched protein tyrosine phosphatase, in schizophrenia and cognitionCocaine-induced changes of synaptic transmission in the striatum are modulated by adenosine A2A receptors and involve the tyrosine phosphatase STEP.Aβ toxicity in Alzheimer's disease.What's hAPPening at synapses? The role of amyloid β-protein precursor and β-amyloid in neurological disorders.A common STEP in the synaptic pathology of diverse neuropsychiatric disorders.TrkB activation by 7, 8-dihydroxyflavone increases synapse AMPA subunits and ameliorates spatial memory deficits in a mouse model of Alzheimer's disease.Molecular underpinnings of neurodegenerative disorders: striatal-enriched protein tyrosine phosphatase signaling and synaptic plasticity."Moonlighting" GAPDH Protein Localizes with AMPA Receptor GluA2 and L1 Axonal Cell Adhesion Molecule at Fiber Cell Borders in the Lens.Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases.Amyloid β oligomers (AβOs) in Alzheimer's disease.Drebrin in Alzheimer's Disease.NMDA glutamate receptor NR1, NR2A and NR2B expression and NR2B Tyr-1472 phosphorylation in the lens.Cellular Receptors of Amyloid β Oligomers (AβOs) in Alzheimer's DiseaseActivation of Phosphotyrosine-Mediated Signaling Pathways in the Cortex and Spinal Cord of SOD1, a Mouse Model of Familial Amyotrophic Lateral Sclerosis
P2860
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P2860
Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Reduced levels of the tyrosine ...... GluA2 receptor internalization
@ast
Reduced levels of the tyrosine ...... GluA2 receptor internalization
@en
Reduced levels of the tyrosine ...... GluA2 receptor internalization
@nl
type
label
Reduced levels of the tyrosine ...... GluA2 receptor internalization
@ast
Reduced levels of the tyrosine ...... GluA2 receptor internalization
@en
Reduced levels of the tyrosine ...... GluA2 receptor internalization
@nl
prefLabel
Reduced levels of the tyrosine ...... GluA2 receptor internalization
@ast
Reduced levels of the tyrosine ...... GluA2 receptor internalization
@en
Reduced levels of the tyrosine ...... GluA2 receptor internalization
@nl
P2093
P2860
P1476
Reduced levels of the tyrosine ...... GluA2 receptor internalization
@en
P2093
George M Anderson
Paul J Lombroso
Pradeep Kurup
Yongfang Zhang
P2860
P304
P356
10.1111/J.1471-4159.2011.07450.X
P407
P577
2011-09-21T00:00:00Z