Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
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Oncogenic senescence: a multi-functional perspective.Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cellsRejuvenating Strategies for Stem Cell-Based Therapies in Aging.Stromal Senescence By Prolonged CDK4/6 Inhibition Potentiates Tumor Growth.Impact of senescence-associated secretory phenotype and its potential as a therapeutic target for senescence-associated diseasesSenescent cells: an emerging target for diseases of ageing.Senescent cell death brings hopes to life.Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2.Senescence and tumor suppression.p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis.Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors.Overcoming Barriers of Age to Enhance Efficacy of Cancer Immunotherapy: The Clout of the Extracellular Matrix.Understanding the tumor immune microenvironment (TIME) for effective therapy.Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1.NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence.miR200-regulated CXCL12β promotes fibroblast heterogeneity and immunosuppression in ovarian cancers.Fibroblasts in the Tumor Microenvironment: Shield or Spear?Various stress stimuli rewire the profile of liver secretome in a p53-dependent manner.CDK4/6 Inhibitors: The Mechanism of Action May Not Be as Simple as Once ThoughtDifferential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs
P2860
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P2860
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Stromal senescence establishes ...... ent that drives tumorigenesis.
@en
type
label
Stromal senescence establishes ...... ent that drives tumorigenesis.
@en
prefLabel
Stromal senescence establishes ...... ent that drives tumorigenesis.
@en
P2093
P2860
P50
P356
P1476
Stromal senescence establishes ...... ment that drives tumorigenesis
@en
P2093
Andras Schaffer
Andrew J Loza
Brett L Knolhoff
Brian A Belt
David G DeNardo
Gregory Longmore
John R Edwards
Kathleen Leahy
Kevin C Flanagan
Megan K Ruhland
P2860
P2888
P356
10.1038/NCOMMS11762
P407
P577
2016-06-08T00:00:00Z