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Accumulation of senescent cells in mitotic tissue of aging primates

Accumulation of senescent cells in mitotic tissue of aging primates

http://www.wikidata.org/entity/Q28274849

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Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging Human RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biology Two faces of p53: aging and tumor suppression Old cells, new tricks: chromatin structure in senescence Cellular Senescence as the Causal Nexus of Aging Protein Oxidation in Aging: Does It Play a Role in Aging Progression?Therapeutic targeting of replicative immortality Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells.Length-dependent processing of telomeres in the absence of telomerase.Physiological and Pathological Aging Affects Chromatin Dynamics, Structure and Function at the Nuclear Edge Aging and radiation: bad companions The aging clock and circadian control of metabolism and genome stability Variation at the TERT locus and predisposition for cancer Methamphetamine accelerates cellular senescence through stimulation of de novo ceramide biosynthesis Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation Changes in gene expression associated with aging commonly originate during juvenile growth GammaH2AX and cancer Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor The Impacts of Cellular Senescence in Elderly Pneumonia and in Age-Related Lung Diseases That Increase the Risk of Respiratory Infections.Quantitative model of cell cycle arrest and cellular senescence in primary human fibroblasts.A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen.Methionine restriction activates the retrograde response and confers both stress tolerance and lifespan extension to yeast, mouse and human cells A two-step model for senescence triggered by a single critically short telomere.Mechanisms and consequences of injury and repair in older organ transplants DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer Senescent cells as a source of inflammatory factors for tumor progression.Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging.The footprint of the ageing stroma in older patients with breast cancer.Inflammatory networks during cellular senescence: causes and consequences.Deep sequencing reveals novel microRNAs and regulation of microRNA expression during cell senescence.Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status.mTOR Signaling from Cellular Senescence to Organismal Aging Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence.Four faces of cellular senescence.Cellular senescence: a link between cancer and age-related degenerative disease?Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.The role of senescent cells in ageing.

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P2860

Accumulation of senescent cells in mitotic tissue of aging primates

http://www.wikidata.org/entity/Q28274849

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2007 nî lūn-bûn

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2007 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2007 թվականի հունվարին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Accumulation of senescent cells in mitotic tissue of aging primates

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Accumulation of senescent cells in mitotic tissue of aging primates

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Accumulation of senescent cells in mitotic tissue of aging primates

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type

label

Accumulation of senescent cells in mitotic tissue of aging primates

@ast

Accumulation of senescent cells in mitotic tissue of aging primates

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Accumulation of senescent cells in mitotic tissue of aging primates

@nl

prefLabel

Accumulation of senescent cells in mitotic tissue of aging primates

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Accumulation of senescent cells in mitotic tissue of aging primates

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Accumulation of senescent cells in mitotic tissue of aging primates

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Mechanisms of Ageing and Development

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Accumulation of senescent cells in mitotic tissue of aging primates

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Jessie C Jeyapalan

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John M Sedivy

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Mark Ferreira

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Utz Herbig

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P2860

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Homologous recombination generates T-loop-sized deletions at human telomeres

Regenerative potential of human skeletal muscle during aging

Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like protein

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

Oxidative stress shortens telomeres

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