Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2 - Wikidata - wikimedia - TriplyDB

Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

http://www.wikidata.org/entity/Q36991056

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Molecular Biology and Clinical Mitigation of Cancer Treatment-Induced Neuropathy Chemotherapy-induced peripheral neurotoxicity and complementary and alternative medicines: progress and perspective FOLFOX/FOLFIRI pharmacogenetics: the call for a personalized approach in colorectal cancer therapy The anti-diabetic drug metformin protects against chemotherapy-induced peripheral neuropathy in a mouse model Noninvasive peroneal sensory and motor nerve conduction recordings in the rabbit distal hindlimb: feasibility, variability and neuropathy measure Multidrug Resistance-Associated Protein 2 (MRP2) Mediated Transport of Oxaliplatin-Derived Platinum in Membrane Vesicles Pathophysiology of Chemotherapy-Induced Peripheral Neuropathy.Herbal Medicine AC591 Prevents Oxaliplatin-Induced Peripheral Neuropathy in Animal Model and Cancer Patients.GLUT1-mediated selective tumor targeting with fluorine containing platinum(II) glycoconjugates Platinum-induced neurotoxicity and preventive strategies: past, present, and future A phosphotyrosine switch regulates organic cation transporters.Conjunctive therapy of cisplatin with the OCT2 inhibitor cimetidine: influence on antitumor efficacy and systemic clearance Cellular uptake of imatinib into leukemic cells is independent of human organic cation transporter 1 (OCT1).Uptake carriers and oncology drug safety.Chemotherapy-induced peripheral neurotoxicity (CIPN): what we need and what we know.Mechanism-based treatment for chemotherapy-induced peripheral neuropathic pain.Mechanisms of distal axonal degeneration in peripheral neuropathies.Role of transporters in the distribution of platinum-based drugs.Discovery of a new method for potent drug development using power function of stoichiometry of homomeric biocomplexes or biological nanomotors Methyl 6-Amino-6-deoxy-d-pyranoside-Conjugated Platinum(II) Complexes for Glucose Transporter (GLUT)-Mediated Tumor Targeting: Synthesis, Cytotoxicity, and Cellular Uptake Mechanism.Reactive oxygen species mediate oxaliplatin-induced epithelial-mesenchymal transition and invasive potential in colon cancer.The Role of Transporters in the Toxicity of Chemotherapeutic Drugs: Focus on Transporters for Organic Cations.Epigenetic activation of the drug transporter OCT2 sensitizes renal cell carcinoma to oxaliplatin.Gut microbiota is critical for the induction of chemotherapy-induced pain.Identification of OAT1/OAT3 as Contributors to Cisplatin Toxicity.Platinum-induced neurotoxicity: A review of possible mechanisms.Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin.Genetic advances uncover mechanisms of chemotherapy-induced peripheral neuropathy.Pharmacotherapy options for managing chemotherapy-induced peripheral neurotoxicity.OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.Evaluation of the Profile and Mechanism of Neurotoxicity of Water-Soluble [Cu(P)4]PF6 and [Au(P)4]PF6 (P = thp or PTA) Anticancer Complexes.OM-LV20, a novel peptide from odorous frog skin, accelerates wound healing in vitro and in vivo.Cathelicidin-OA1, a novel antioxidant peptide identified from an amphibian, accelerates skin wound healing.Oxaliplatin-induced blood brain barrier loosening: a new point of view on chemotherapy-induced neurotoxicity.Modulating Chemosensitivity of Tumors to Platinum-Based Antitumor Drugs by Transcriptional Regulation of Copper Homeostasis.Interaction of the New Monofunctional Anticancer Agent Phenanthriplatin With Transporters for Organic Cations.

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Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

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Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

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Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

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Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

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Proceedings of the National Academy of Sciences of the United States of America

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Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

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Alice A Gibson

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Anthony F Shields

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Cynthia S Lancaster

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Guoqing Du

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Hugh Giovinazzo

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Laura J Janke

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P2860

Differential expression of ATP7A, ATP7B and CTR1 in adult rat dorsal root ganglion tissue

Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions.

Differential transport of platinum compounds by the human organic cation transporter hOCT2 (hSLC22A2).

Dose effects of oxaliplatin on persistent and transient Na+ conductances and the development of neurotoxicity.

Clinical pharmacokinetics of oxaliplatin: a critical review.

Oral poly(ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity

Multimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in mice

Influence of Oct1/Oct2-deficiency on cisplatin-induced changes in urinary N-acetyl-beta-D-glucosaminidase.

Relationships between hydrophobicity, reactivity, accumulation and peripheral nerve toxicity of a series of platinum drugs.

Platinum neurotoxicity pharmacogenetics

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110

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Giuliano Ciarimboli

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2013-06-17T00:00:00Z

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239945540

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