Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage
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2013 Dade W. Moeller lecture: medical countermeasures against radiological terrorismSOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathwaysAEOL 10150 Mitigates Radiation-Induced Lung Injury in the Nonhuman Primate: Morbidity and Mortality are Administration Schedule-Dependent.Immunological Aspect of Radiation-Induced Pneumonitis, Current Treatment Strategies, and Future ProspectsDietary flaxseed administered post thoracic radiation treatment improves survival and mitigates radiation-induced pneumonopathy in mice.Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potentialRational design of superoxide dismutase (SOD) mimics: the evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents.Paradoxical relationship between Mn superoxide dismutase deficiency and radiation-induced cognitive defects.Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.Radiation mitigating properties of the lignan component in flaxseedMitigation of radiation-induced lung injury by genistein and EUK-207.Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimicsRadiation damage to the lung: mitigation by angiotensin-converting enzyme (ACE) inhibitorsMitigation of lung injury after accidental exposure to radiation.Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumorsMn(III) meso-tetrakis-(N-ethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression.Dose-modifying factor for captopril for mitigation of radiation injury to normal lungThe antioxidant, MnTE-2-PyP, prevents side-effects incurred by prostate cancer irradiation.Novel Manganese-Porphyrin Superoxide Dismutase-Mimetic Widens the Therapeutic Margin in a Preclinical Head and Neck Cancer Model.Anticancer therapeutic potential of Mn porphyrin/ascorbate systemMitigation of radiation-induced lung injury with EUK-207 and genistein: effects in adolescent ratsTemporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lungA combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon.Short-term treatment with a SOD/catalase mimetic, EUK-207, mitigates pneumonitis and fibrosis after single-dose total-body or whole-thoracic irradiationSubcutaneous administration of bovine superoxide dismutase protects lungs from radiation-induced lung injury.Impact of SOD-Mimetic Manganoporphyrins on Spin Trapping of Superoxide and Related Artifacts.Changing the energy of an immune responseComprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+.Salen Mn complexes mitigate radiation injury in normal tissues.MnTnBuOE-2-PyP protects normal colorectal fibroblasts from radiation damage and simultaneously enhances radio/chemotherapeutic killing of colorectal cancer cellsSuperoxide dismutase mimic, MnTE-2-PyP(5+) ameliorates acute and chronic proctitis following focal proton irradiation of the rat rectum.Enalapril mitigates radiation-induced pneumonitis and pulmonary fibrosis if started 35 days after whole-thorax irradiation.Antioxidant therapeutics: Pandora's box.Redox-modulated phenomena and radiation therapy: the central role of superoxide dismutases.Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+).Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.Therapeutic potential of peroxynitrite decomposition catalysts: a patent review.The protective effects of trace elements against side effects induced by ionizing radiationEvaluation of the anti-oxidant properties of a SOD-mimic Mn-complex in activated macrophages.Potential for a novel manganese porphyrin compound as adjuvant canine lymphoma therapy.
P2860
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P2860
Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Early and late administration ...... radiation-induced lung damage
@en
type
label
Early and late administration ...... radiation-induced lung damage
@en
prefLabel
Early and late administration ...... radiation-induced lung damage
@en
P2093
P2860
P1476
Early and late administration ...... radiation-induced lung damage
@en
P2093
Benjamin Gauter-Fleckenstein
Chen Jiang
Ines Batinic-Haberle
Katharina Fleckenstein
Kouros Owzar
Zeljko Vujaskovic
P2860
P304
P356
10.1016/J.FREERADBIOMED.2010.01.020
P577
2010-01-20T00:00:00Z