Endothelial cell protein C receptor acts as a cellular receptor for factor VIIa on endothelium.
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FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy menInflammation, obesity, and thrombosisEndothelial protein C receptor function in murine and human breast cancer developmentStructural and Functional Studies of γ-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological CalciumFactor VIIa interaction with endothelial cells and endothelial cell protein C receptor.Bio-distribution of pharmacologically administered recombinant factor VIIa (rFVIIa)Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) ConsortiumFactor VIIa binding to endothelial cell protein C receptor protects vascular barrier integrity in vivo.Cystine 186-cystine 209 disulfide bond is not essential for the procoagulant activity of tissue factor or for its de-encryptionZinc modulates the interaction of protein C and activated protein C with endothelial cell protein C receptorEndothelial cell protein C receptor: a multiliganded and multifunctional receptorInhibitory effects of oroxylin A on endothelial protein C receptor shedding in vitro and in vivo.The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors.Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIaFactor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection.Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis).Coagulation factor Xa cleaves protease-activated receptor-1 and mediates signaling dependent on binding to the endothelial protein C receptor.Group V secretory phospholipase A2 impairs endothelial protein C receptor-dependent protein C activation and accelerates thrombosis in vivo.Inactivation of factor VIIa by antithrombin in vitro, ex vivo and in vivo: role of tissue factor and endothelial cell protein C receptor.The endothelial protein C receptor (PROCR) Ser219Gly variant and risk of common thrombotic disorders: a HuGE review and meta-analysis of evidence from observational studies.Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery diseasePlasmodium falciparum adhesion domains linked to severe malaria differ in blockade of endothelial protein C receptor.The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells.Endothelial cell protein C receptor-mediated redistribution and tissue-level accumulation of factor VIIa.Early rise in circulating endothelial protein C receptor correlates with poor outcome in severe sepsisHeterozygous congenital Factor VII deficiency with the 9729del4 mutation, associated with severe spontaneous intracranial bleeding in an adolescent maleFunctional properties and active-site topographies of factor X Gla- and prothrombin Gla-domain chimeras of activated protein CFactor VIIa binding to endothelial cell protein C receptor.Mechanisms of anticoagulant and cytoprotective actions of the protein C pathway.Matriptase activation connects tissue factor-dependent coagulation initiation to epithelial proteolysis and signalingFactor VIIa interaction with tissue factor and endothelial cell protein C receptor on cell surfaces.Endothelial cell protein C receptor cellular localization and trafficking: potential functional implications.Lack of association of soluble endothelial protein C receptor and PROCR 6936A/G polymorphism with the risk of venous thromboembolism in a prospective study.Intrapleural Adenoviral-mediated Endothelial Cell Protein C Receptor Gene Transfer Suppresses the Progression of Malignant Pleural Mesothelioma in a Mouse Model.Tissue factor is an angiogenic-specific receptor for factor VII-targeted immunotherapy and photodynamic therapy.Tissue factor and cell signalling in cancer progression and thrombosis.The endothelial cell protein C receptor: cell surface conductor of cytoprotective coagulation factor signaling.Current knowledge on the genetics of incident venous thrombosis.A novel protein C-factor VII chimera provides new insights into the structural requirements for cytoprotective PAR1 signaling.Targeting clotting proteins in cancer therapy - progress and challenges.
P2860
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P2860
Endothelial cell protein C receptor acts as a cellular receptor for factor VIIa on endothelium.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Endothelial cell protein C rec ...... or factor VIIa on endothelium.
@en
type
label
Endothelial cell protein C rec ...... or factor VIIa on endothelium.
@en
prefLabel
Endothelial cell protein C rec ...... or factor VIIa on endothelium.
@en
P2093
P2860
P356
P1476
Endothelial cell protein C rec ...... or factor VIIa on endothelium.
@en
P2093
Anne Steinoe
Charles T Esmon
L Vijaya Mohan Rao
Samit Ghosh
Usha R Pendurthi
P2860
P304
11849-11857
P356
10.1074/JBC.M609283200
P407
P577
2007-02-27T00:00:00Z