Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1 - Wikidata - wikimedia - TriplyDB

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

http://www.wikidata.org/entity/Q36998199

about

Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics Qualitative de novo analysis of full length cDNA and quantitative analysis of gene expression for common marmoset (Callithrix jacchus) transcriptomes using parallel long-read technology and short-read sequencing Cyanobacterial Toxins of the Laurentian Great Lakes, Their Toxicological Effects, and Numerical Limits in Drinking Water Ontogeny of human hepatic and intestinal transporter gene expression during childhood: age matters.Frequencies of two functionally significant SNPs and their haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in six ethnic groups of Pakistani population.Mechanisms and assessment of statin-related muscular adverse effects.Histogram analysis of gadoxetic acid-enhanced MRI for quantitative hepatic fibrosis measurement A semi-physiologically based pharmacokinetic pharmacodynamic model for glycyrrhizin-induced pseudoaldosteronism and prediction of the dose limit causing hypokalemia in a virtual elderly population.Zebrafish Oatp-mediated transport of microcystin congeners.OATP1B1 and tumour OATP1B3 modulate exposure, toxicity, and survival after irinotecan-based chemotherapy ABCB1 polymorphism is associated with atorvastatin-induced liver injury in Japanese population.Determinants of post-prandial plasma bile acid kinetics in human volunteers.Effect of SLCO1B1 Polymorphisms on Rifabutin Pharmacokinetics in African HIV-Infected Patients with Tuberculosis.Inherited variation in OATP1B1 is associated with treatment outcome in acute myeloid leukemia.Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver Functional analysis of novel polymorphisms in the human SLCO1A2 gene that encodes the transporter OATP1A2 Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis.More Power to OATP1B1: An Evaluation of Sample Size in Pharmacogenetic Studies Using a Rosuvastatin PBPK Model for Intestinal, Hepatic, and Renal Transporter-Mediated Clearances.Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sex The regulation of human hepatic drug transporter expression by activation of xenobiotic-sensing nuclear receptors.Current status and recent advances of next generation sequencing techniques in immunological repertoire.Functional characterization of common protein variants in the efflux transporter ABCC11 and identification of T546M as functionally damaging variant.Impact of Transporter Polymorphisms on Drug Development: Is It Clinically Significant?Resveratrol and its major sulfated conjugates are substrates of organic anion transporting polypeptides (OATPs): impact on growth of ZR-75-1 breast cancer cells.Interindividual and interethnic variability in drug disposition: polymorphisms in organic anion transporting polypeptide 1B1 (OATP1B1; SLCO1B1).Chinese biobanks: present and future.Ontogeny of Hepatic Drug Transporters as Quantified by LC-MS/MS Proteomics.Ecological population genomics in the marine environment.Heritability of metoprolol and torsemide pharmacokinetics.Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations.Identification of the effect of multiple polymorphisms on the pharmacokinetics of simvastatin and simvastatin acid using a population-modeling approach.Association of Tissue Abiraterone Levels and SLCO Genotype with Intraprostatic Steroids and Pathologic Response in Men with High-Risk Localized Prostate Cancer.Identification of two novel genes SLC15A2 and SLCO1B3 associated with maintenance dose variability of warfarin in a Chinese population.Effect modification by region in the associations of LEP G2548A and LEPR Q223R polymorphisms with statin-induced CK elevation.Transporter expression in non-cancerous and cancerous liver tissue from donors with hepatocellular carcinoma and chronic hepatitis C infection quantified by LC-MS/MS proteomics.Inter-Subject Variability in OCT1 Activity in 27 Batches of Cryopreserved Human Hepatocytes and Association with OCT1 mRNA Expression and Genotype.Comprehensive Pharmacogenomic Study Reveals an Important Role of UGT1A3 in Montelukast Pharmacokinetics.Reproductive management through integration of PGD and MPS-based noninvasive prenatal screening/diagnosis for a family with GJB2-associated hearing impairment.SLCO1B1 521T > C polymorphism associated with rosuvastatin-induced myotoxicity in Chinese coronary artery disease patients: a nested case-control study.Association between statin-induced creatine kinase elevation and genetic polymorphisms in SLCO1B1, ABCB1 and ABCG2.

P2860

Q26786582-E537B32B-42E8-40BA-BCFB-00C37092E8A4 Q28540182-1FA2CC35-551D-46F0-B0DD-3B878FC9B760 Q33833344-760CADB2-3407-4B1E-85B1-4931224EA8AD Q33942993-8E9F3696-3393-4CD5-A6C3-6FCE1F569C36 Q34065757-3128FBE2-F0B8-42A4-9825-2AA58E5BD084 Q34570995-F1884F7C-39DD-4DE0-897D-17916CA37369 Q34612486-0A327E15-73A3-45A5-8F9C-B79C4D9B6D2F Q35478170-B178D5DC-850E-48D7-BA63-7D76EB9410FF Q35657461-26D3BE9A-09A8-42F3-9402-D092A74684D1 Q35678729-C15269D0-0856-48AE-A75A-A9C499D0D72C Q36050960-C56F0C92-E0B2-463C-9896-6A252DF9D235 Q36414100-553F77C5-4881-4169-8938-4EAAB1F39424 Q36439164-832EEA06-77C4-48D3-9BDF-C264ADEFFF2E Q36981855-AD053F15-B967-4E7B-813B-39186C70AC2A Q37062634-561A4186-6BE2-4D18-81B4-8621813A7928 Q37207831-467408D1-9217-471E-B20A-514FD8D11792 Q37279044-51630344-AA0D-413C-97AE-51F7D1A02412 Q37394474-3B463EBD-7A30-4372-BBFB-5A72A810E517 Q37422685-527C061C-49BB-4551-AB67-23E4AD5F02C2 Q38750759-78844EA2-8539-42AB-9CAA-8BBEC2053646 Q38768307-35E3A303-EEDB-44F5-8969-238D5F111FED Q38884180-7BD10BF6-D661-46C5-A292-8536CA459584 Q38888369-77EE72C3-81FE-424C-B04F-026AC6B6FDEA Q38977944-44385AF5-4428-48EC-B8F0-CAAC852FA33A Q39034284-B5557160-6453-4029-9E8D-2E1516E859C5 Q39231340-677D8564-DBDE-4699-A187-125778A9913F Q39683666-9553FA49-F946-4CFF-95A0-1991C8553FD0 Q39864227-8731078B-BCC4-44BD-B001-969F6A54812B Q41398712-33B46066-6B3B-4A4E-BFAF-FB8D00E411B3 Q41706349-0BF2911D-F431-401D-9563-2B5DA18507C6 Q43965937-87313337-BF1C-49EC-9E3F-A13AEF7CC5ED Q45988129-2C44E1B9-0285-4ECD-A97B-859B62898AD4 Q47113473-ECAB6ACE-A732-4B64-842F-FB8071578013 Q47342360-2892F220-F3EE-49EB-8F08-35573708B7A4 Q47402203-DE9237F9-ED1F-4448-ACA1-26564FE75AF2 Q47808595-7A3E1813-FE01-471A-A896-4D565A68EE16 Q49903283-3495D5E8-5717-4495-BB3C-C0808E3523FD Q50351727-FA8D0272-F050-4A7A-9712-A7F0D2B2F691 Q53099880-1755B132-D842-4FDF-AFE0-2C1098EA4FED Q54373168-418CEC0C-E974-4774-9EC0-B81E01C59FCB

P2860

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

http://www.wikidata.org/entity/Q36998199

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Genetics is a major determinan ...... but not of OATP1B3 and OATP2B1

@en

type

label

Genetics is a major determinan ...... but not of OATP1B3 and OATP2B1

@en

prefLabel

Genetics is a major determinan ...... but not of OATP1B3 and OATP2B1

@en

P1433

Q36998199-EE0B5752-1905-4E19-BF16-F3F806932B60

P1476

Q36998199-815FF7EE-6448-4E27-8466-145A634DFE4D

P2093

Q36998199-33ED81EC-02FA-473F-9CF9-815B82684506

Q36998199-348001C7-673D-4793-8DC7-6C4362BE3147

Q36998199-4965CEA6-116C-4F50-A706-56B47A34A987

Q36998199-54060C3A-840C-4C28-B306-1AD4D1B59463

Q36998199-9C4BB81A-32E7-4998-9481-5CBF477C1813

Q36998199-C64E9429-2466-4D97-8C45-ECFDF4F2A770

P2860

Q36998199-00535325-B072-43A4-B109-25B800017E95

Q36998199-0103EF62-496D-41BF-8B75-48220977DDCC

Q36998199-01059E22-6DAA-4BEB-9673-CC5EB51D635D

Q36998199-04EF6A3C-58AF-46F9-9E83-76CE8B19A9A7

Q36998199-050F5010-B3DF-45EF-A7B1-7A0B885A7275

Q36998199-07EA1141-617C-4E42-AA77-CDBED2469501

Q36998199-0A6FBF1E-9434-4263-9F83-50DFFD67B2A1

Q36998199-0EE541E6-E04E-4FCD-9670-499B3BEE1364

Q36998199-10CC635C-7870-4A7E-A8D1-FE8EB8D8CE58

Q36998199-12C7433D-5DF3-4DB8-9F9B-5AE820F095C1

P2888

Q36998199-7D9871C9-B713-4278-A4EF-996562F02E1B

P304

Q36998199-BF065866-B8C1-459E-88C3-77F765D87C7E

P31

Q36998199-18154C2C-5EAB-4D93-B78F-6BCA42AFEB95

P356

Q36998199-F115C54D-4DCB-4939-BEEF-331D62449498

P433

Q36998199-A706DE88-6132-4938-9147-6C181C9134F5

P478

Q36998199-5F450FCB-AC92-49FB-A99D-9C8DF68D0A50

P50

Q36998199-114C6B2B-6874-41B6-ABFF-94154A84CD91

Q36998199-7C8B9D61-620A-4F3D-93CA-265E81C60961

P577

Q36998199-CC0E025B-47D2-4E84-909D-CA0FAC99340A

P5875

Q36998199-4E3ACDBD-007D-4427-8E29-55C1A7225649

P6179

Q36998199-5A7F2943-5D6D-491A-B3DB-DD8D7DB016FF

P698

Q36998199-D3EF4008-943F-4195-8FED-BE7DAC09ACCE

P932

Q36998199-2C3D1F14-9E96-494C-9221-8B33AA27A9FB

P356

P1433

Genome Medicine

P1476

Genetics is a major determinan ...... but not of OATP1B3 and OATP2B1

@en

P2093

Anne T Nies

http://www.w3.org/2001/XMLSchema#string

Bruno Stieger

http://www.w3.org/2001/XMLSchema#string

Matthias Schwab

http://www.w3.org/2001/XMLSchema#string

Mikko Niemi

http://www.w3.org/2001/XMLSchema#string

Oliver Burk

http://www.w3.org/2001/XMLSchema#string

Stefan Winter

http://www.w3.org/2001/XMLSchema#string

P2860

Mfold web server for nucleic acid folding and hybridization prediction

A note on exact tests of Hardy-Weinberg equilibrium

Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure

A method and server for predicting damaging missense mutations

Haploview: analysis and visualization of LD and haplotype maps

A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane

Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans

Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1 alpha

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

P2888

P304

1

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1186/GM405

http://www.w3.org/2001/XMLSchema#string

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

5

http://www.w3.org/2001/XMLSchema#string

P50

Elke Schaeffeler

Ulrich M. Zanger

P577

2013-01-11T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

234121068

http://www.w3.org/2001/XMLSchema#string

P6179

1042062406

http://www.w3.org/2001/XMLSchema#string

P698

23311897

http://www.w3.org/2001/XMLSchema#string

P932

3706890

http://www.w3.org/2001/XMLSchema#string