A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure - Wikidata - wikimedia - TriplyDB

A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure

A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure

http://www.wikidata.org/entity/Q37000342

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Loss-of-function DNA sequence variant in the CLCNKA chloride channel implicates the cardio-renal axis in interindividual heart failure risk variation G Protein-Coupled Receptor Kinases: Crucial Regulators of Blood Pressure GRK2 in the heart: a GPCR kinase and beyond Pharmacogenetics in chronic heart failure: new developments and current challenges Pharmacogenomics and cardiovascular disease Graves' disease presenting as bi-ventricular heart failure with severe pulmonary hypertension and pre-eclampsia in pregnancy--a case report and review of the literature Clinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementation Pharmacogenomics of hypertension and heart disease Atomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor Kinases Language: Disputed definitions Mapping genetic variants associated with beta-adrenergic responses in inbred mice An antagonism between the AKT and beta-adrenergic signaling pathways mediated through their reciprocal effects on miR-199a-5p The A's, G's, C's, and T's of health disparities Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.The expanding GRK interactome: Implications in cardiovascular disease and potential for therapeutic development.Social Determinants of Racial Disparities in CKD.Views on personalized medicine: do the attitudes of African American and white prescription drug consumers differ?Molecular assembly of rhodopsin with G protein-coupled receptor kinases.Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans.Peripartum cardiomyopathy among cardiovascular patients referred for echocardiography at Parirenyatwa Teaching Hospital, Harare, Zimbabwe Pharmacogenomics of beta1-adrenergic receptor polymorphisms in heart failure.Association of a common KCNE1 variant with heart failure Rescue of familial cardiomyopathies by modifications at the level of sarcomere and Ca2+ fluxes.β-Adrenergic receptor subtype signaling in heart: from bench to bedside.Applied pharmacogenomics in cardiovascular medicine Genotype-based risk and pharmacogenetic sampling in clinical trials Association of an intronic, but not any exonic, FRMD4B sequence variant and heart failure Discussing race-related limitations of genomic testing for colon cancer risk: implications for education and counseling.Common variants in HSPB7 and FRMD4B associated with advanced heart failure Length of day during early gestation as a predictor of risk for severe retinopathy of prematurity.Overlapping and opposing functions of G protein-coupled receptor kinase 2 (GRK2) and GRK5 during heart development.Functional selectivity in adrenergic and angiotensin signaling systems.RAAS and adrenergic genes in heart failure: Function, predisposition and survival implications Emerging clinical applications in cardiovascular pharmacogenomics.Targeting G protein-coupled receptor kinases (GRKs) in Heart Failure.Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients.Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process.β₂ AR agonists in treatment of chronic heart failure: long path to translation.G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers

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A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure

http://www.wikidata.org/entity/Q37000342

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 20 April 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

A GRK5 polymorphism that inhib ...... is protective in heart failure

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A GRK5 polymorphism that inhib ...... s protective in heart failure.

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A GRK5 polymorphism that inhib ...... is protective in heart failure

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A GRK5 polymorphism that inhib ...... s protective in heart failure.

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A GRK5 polymorphism that inhib ...... is protective in heart failure

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A GRK5 polymorphism that inhib ...... s protective in heart failure.

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Nature Medicine

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A GRK5 polymorphism that inhib ...... is protective in heart failure

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Abhinav Diwan

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Faisal M Syed

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Gerald W Dorn

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Harvey S Hahn

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Jeffrey S Martini

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Li Sparks

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Reagan J Kelly

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Rohan R Parekh

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Scot J Matkovich

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Sharon Cresci

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Inference of population structure using multilocus genotype data

Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

Regulation of cardiac contractility by Rab4-modulated beta2-adrenergic receptor recycling.

Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling.

beta-adrenergic receptor blockade in chronic heart failure.

Beta-adrenergic receptor blockade arrests myocyte damage and preserves cardiac function in the transgenic G(salpha) mouse

Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure.

Beta-adrenergic receptors in the failing heart: the good, the bad, and the unknown.

Current role of beta-adrenergic blockers in the management of chronic heart failure.

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510-517

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scholarly article

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10.1038/NM1750

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5

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14

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John A. Spertus

Sharon L R Kardia

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2008-04-20T00:00:00Z

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5427868

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18425130

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2596476

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