Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice. - Wikidata - wikimedia - TriplyDB

Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice.

Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice.

http://www.wikidata.org/entity/Q37000605

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NEDD9 promotes oncogenic signaling in mammary tumor development.Platelets and their role in cancer evolution and immune system Activation of blood coagulation in cancer: implications for tumour progression Endothelial protein C receptor function in murine and human breast cancer development Proteinase-Activated Receptor 2 Is a Novel Regulator of TGF-β Signaling in Pancreatic Cancer PRSS3 is a prognostic marker in invasive ductal carcinoma of the breast.Tissue factor and PAR2 signaling in the tumor microenvironment Tumors, ticks and tissue factor.The many faces of tissue factor.Evidence for tissue factor phosphorylation and its correlation with protease-activated receptor expression and the prognosis of primary breast cancer.Engineering of substrate selectivity for tissue factor.factor VIIa complex signaling through protease-activated receptor 2.Ixolaris, a tissue factor inhibitor, blocks primary tumor growth and angiogenesis in a glioblastoma model.Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109 The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2.Protease-activated receptors mediate crosstalk between coagulation and fibrinolysis.Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development.Breast cancer phenotypes regulated by tissue factor-factor VII pathway: Possible therapeutic targets.Role of the protein C receptor in cancer progression.Thrombin drives tumorigenesis in colitis-associated colon cancer MicroRNA-34a mediates the autocrine signaling of PAR2-activating proteinase and its role in colonic cancer cell proliferation.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.Orthotopic injection of breast cancer cells into the mammary fat pad of mice to study tumor growth.Protease Activated Receptors 1 and 2 Correlate Differently with Breast Cancer Aggressiveness Depending on Tumor ER Status Inhibition of tissue factor by ixolaris reduces primary tumor growth and experimental metastasis in a murine model of melanoma The tick-derived inhibitor Ixolaris prevents tissue factor signaling on tumor cells.Proteinase-activated receptor 2 promotes cancer cell migration through RNA methylation-mediated repression of miR-125b.PH motifs in PAR1&2 endow breast cancer growth.Colon Cancer Growth and Dissemination Relies upon Thrombin, Stromal PAR-1, and Fibrinogen.Matriptase activation connects tissue factor-dependent coagulation initiation to epithelial proteolysis and signaling Proteinase-activated receptor 2 (PAR2) in hepatic stellate cells - evidence for a role in hepatocellular carcinoma growth in vivo Tissue factor in cancer progression and angiogenesis.Role of tissue factor in cancer.Alternatively spliced tissue factor induces angiogenesis through integrin ligation.Hepatocyte nuclear factor-4-independent synthesis of coagulation factor VII in breast cancer cells and its inhibition by targeting selective histone acetyltransferases Metastatic site-specific polarization of macrophages in intracranial breast cancer metastases.Teleocidin A2 inhibits human proteinase-activated receptor 2 signaling in tumor cells.Platelets: linking hemostasis and cancer.Tissue factor and cell signalling in cancer progression and thrombosis.Tissue factor and cancer.Regulation of vascular function on posttranscriptional level.

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Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice.

http://www.wikidata.org/entity/Q37000605

description

article científic

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article scientifique

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articolo scientifico

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bilimsel makale

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scientific article published on September 2008

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vedecký článok

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vetenskaplig artikel

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vědecký článek

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Protease-activated receptor (P ...... noma in polyoma middle T mice.

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Protease-activated receptor (P ...... noma in polyoma middle T mice.

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Protease-activated receptor (P ...... noma in polyoma middle T mice.

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Protease-activated receptor (P ...... noma in polyoma middle T mice.

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0008-5472.CAN-08-0419

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Cancer Research

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Protease-activated receptor (P ...... noma in polyoma middle T mice.

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Barbara M Mueller

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Florence Schaffner

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Henri H Versteeg

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Lesley G Ellies

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Marjolein Kerver

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Patricia Andrade-Gordon

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Wolfram Ruf

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P2860

Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2

Thrombin receptor overexpression in malignant and physiological invasion processes

Enhanced tumor-forming capacity for immortalized melanocytes expressing melanoma growth stimulatory activity/growth-regulated cytokine beta and gamma proteins

Signaling of the tissue factor coagulation pathway in angiogenesis and cancer

Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis

Proangiogenic effects of protease-activated receptor 2 are tumor necrosis factor-alpha and consecutively Tie2 dependent

Genes that mediate breast cancer metastasis to lung

Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

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