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A survey of current trends in computational drug repositioningReactive Oxygen Species-Mediated Mechanisms of Action of Targeted Cancer TherapyDrug repurposing identifies a synergistic combination therapy with imatinib mesylate for gastrointestinal stromal tumor.In vitro screening for drug repositioning.Beyond standard therapy: drugs under investigation for the treatment of gastrointestinal stromal tumor.Auranofin induces apoptosis by ROS-mediated ER stress and mitochondrial dysfunction and displayed synergistic lethality with piperlongumine in gastric cancerAuranofin-mediated inhibition of PI3K/AKT/mTOR axis and anticancer activity in non-small cell lung cancer cells.In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma.GIST treatment options after tyrosine kinase inhibitors.Clinically Evaluated Cancer Drugs Inhibiting Redox Signaling.Peptide protected gold clusters: chemical synthesis and biomedical applications.Flunarizine rescues reduced lifespan in CLN3 triple knock-out Caenorhabditis elegans model of batten disease.Auranofin: repurposing an old drug for a golden new age.Drug repurposing in idiopathic pulmonary fibrosis filtered by a bioinformatics-derived composite score.Restoring microenvironmental redox and pH homeostasis inhibits neoplastic cell growth and migration: therapeutic efficacy of esomeprazole plus sulfasalazine on 3-MCA-induced sarcoma.Expression of CD117, DOG-1, and IGF-1R in gastrointestinal stromal tumours - an analysis of 70 cases from 2004 to 2010.Selection and characterization of a human ovarian cancer cell line resistant to auranofin.Elimination of stem-like cancer cell side-population by auranofin through modulation of ROS and glycolysis.Comparative oncology approach to drug repurposing in osteosarcoma.Developing a genetic signature to predict drug response in ovarian cancer.Trypanocidal Effects of Cisplatin alone and in Combination with Nigella sativa Oil on Experimentally Infected Mice with Trypanosoma evansi.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 May 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Drug repurposing for gastrointestinal stromal tumor.
@en
Drug repurposing for gastrointestinal stromal tumor.
@nl
type
label
Drug repurposing for gastrointestinal stromal tumor.
@en
Drug repurposing for gastrointestinal stromal tumor.
@nl
prefLabel
Drug repurposing for gastrointestinal stromal tumor.
@en
Drug repurposing for gastrointestinal stromal tumor.
@nl
P2093
P2860
P1476
Drug repurposing for gastrointestinal stromal tumor.
@en
P2093
Andrew K Godwin
Geetika Sethi
Melinda A Broward
Scott J Weir
Ziyan Y Pessetto
P2860
P304
P356
10.1158/1535-7163.MCT-12-0968
P577
2013-05-08T00:00:00Z