Cloning of the low-affinity murine granulocyte-macrophage colony-stimulating factor receptor and reconstitution of a high-affinity receptor complex.
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The SWI/SNF protein ATRX co-regulates pseudoautosomal genes that have translocated to autosomes in the mouse genomeSignal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common beta subunit responsible for different signalingA critical cytoplasmic domain of the interleukin-5 (IL-5) receptor alpha chain and its function in IL-5-mediated growth signal transductionDifferential divergence of three human pseudoautosomal genes and their mouse homologs: implications for sex chromosome evolutionReconstitution of the functional receptors for murine and human interleukin 5The alpha subunit of the granulocyte-macrophage colony-stimulating factor receptor interacts with c-Kit and inhibits c-Kit signalingCharacterisation of the expression and function of the GM-CSF receptor alpha-chain in miceIL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases.Specificity of signaling by hematopoietic cytokine receptors: instructive versus permissive effects.Cytoplasmic domains of the common beta-chain of the GM-CSF/IL-3/IL-5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines.PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors.Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell deathThe GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling.Membrane-associated and soluble granulocyte/macrophage-colony-stimulating factor receptor alpha subunits are independently regulated in HL-60 cellsHistidine-367 of the human common beta chain of the receptor is critical for high-affinity binding of human granulocyte-macrophage colony-stimulating factor.The alpha subunit of the human granulocyte-macrophage colony-stimulating factor receptor signals for glucose transport via a phosphorylation-independent pathwayCross-talk between ICAM-1 and granulocyte-macrophage colony-stimulating factor receptor signaling modulates eosinophil survival and activation.Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory Cytokine: Implications for Immune Therapy.Leukocyte response integrin and integrin-associated protein act as a signal transduction unit in generation of a phagocyte respiratory burst.The zinc finger transcription factor Egr-1 potentiates macrophage differentiation of hematopoietic cellsThe murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit gene.Detailed analysis of the IL-5-IL-5R alpha interaction: characterization of crucial residues on the ligand and the receptor.CBL linker region and RING finger mutations lead to enhanced granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling via elevated levels of JAK2 and LYN.Orf virus encodes a novel secreted protein inhibitor of granulocyte-macrophage colony-stimulating factor and interleukin-2.Sequential mutations in the interleukin-3 (IL3)/granulocyte-macrophage colony-stimulating factor/IL5 receptor beta-subunit genes are necessary for the complete conversion to growth autonomy mediated by a truncated beta C subunit.A membrane-proximal region of the interleukin-2 receptor gamma c chain sufficient for Jak kinase activation and induction of proliferation in T cells.Cytokine-mediated cPLA(2) phosphorylation is regulated by multiple MAPK family members.A cell type-specific constitutive point mutant of the common beta-subunit of the human granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3, and IL-5 receptors requires the GM-CSF receptor alpha-subunit for activation.Macrophage colony-stimulating factor augments beta-amyloid-induced interleukin-1, interleukin-6, and nitric oxide production by microglial cells.The macrosialin promoter directs high levels of transcriptional activity in macrophages dependent on combinatorial interactions between PU.1 and c-Jun.Functional replacement of cytokine receptor extracellular domains by leucine zippers.Understanding the dendritic cell lineage through a study of cytokine receptors.Molecular determinants of the granulocyte-macrophage colony-stimulating factor receptor complex assembly.Multi-colony stimulating activity of interleukin 5 (IL-5) on hematopoietic progenitors from transgenic mice that express IL-5 receptor alpha subunit constitutively.Granulocyte-macrophage colony-stimulating factor promotes glucose transport and blastomere viability in murine preimplantation embryos.Rational design of a mouse granulocyte macrophage-colony-stimulating factor receptor antagonist.Rapid evolution of human pseudoautosomal genes and their mouse homologs.Molecular cloning, sequencing and structural studies of granulocyte-macrophage colony-stimulating factor (GM-CSF) from Indian water buffalo (Bubalus bubalis).Granulocyte-macrophage colony-stimulating factor (GM-CSF): a chemoattractive agent for murine leukocytes in vivo.
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P2860
Cloning of the low-affinity murine granulocyte-macrophage colony-stimulating factor receptor and reconstitution of a high-affinity receptor complex.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1992
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cloning of the low-affinity mu ...... igh-affinity receptor complex.
@en
Cloning of the low-affinity mu ...... igh-affinity receptor complex.
@nl
type
label
Cloning of the low-affinity mu ...... igh-affinity receptor complex.
@en
Cloning of the low-affinity mu ...... igh-affinity receptor complex.
@nl
prefLabel
Cloning of the low-affinity mu ...... igh-affinity receptor complex.
@en
Cloning of the low-affinity mu ...... igh-affinity receptor complex.
@nl
P2093
P2860
P356
P1476
Cloning of the low-affinity mu ...... igh-affinity receptor complex.
@en
P2093
Morrissey PJ
Sorensen R
P2860
P304
P356
10.1073/PNAS.89.10.4295
P407
P577
1992-05-01T00:00:00Z