A possible mechanism of insulin resistance in the rat adipose cell in streptozotocin-induced diabetes mellitus. Depletion of intracellular glucose transport systems
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Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic ratsNormalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression.Sodium-hydrogen exchange and glucose transport in renal microvillus membrane vesicles from rats with diabetes mellitus.Insulin receptor down-regulation is linked to an insulin-induced postreceptor defect in the glucose transport system in rat adipocytesDistribution of glucose transporters in membrane fractions isolated from human adipose cells. Relation to cell size.Regulation of glucose utilization in adipose cells and muscle after long-term experimental hyperinsulinemia in ratsAn in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjectsDivergent mechanisms for the insulin resistant and hyperresponsive glucose transport in adipose cells from fasted and refed rats. Alterations in both glucose transporter number and intrinsic activity.Mechanism for enhanced glucose transport response to insulin in adipose cells from chronically hyperinsulinemic rats. Increased translocation of glucose transporters from an enlarged intracellular poolGlucose transport and metabolism in adipocytes from newly diagnosed untreated insulin-dependent diabetics. Severely impaired basal and postinsulin binding activitiesCoordinate regulation of glucose transporter function, number, and gene expression by insulin and sulfonylureas in L6 rat skeletal muscle cellsRelationships between insulin secretion, insulin action, and fasting plasma glucose concentration in nondiabetic and noninsulin-dependent diabetic subjects.Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitusDifferential regulation of multiple hepatic protein tyrosine phosphatases in alloxan diabetic rats.Insulin resistance in obese Zucker rat (fa/fa) skeletal muscle is associated with a failure of glucose transporter translocationHepatic phosphotyrosine phosphatase activity and its alterations in diabetic rats.Mechanism of insulin-resistant glucose transport activity in the enlarged adipose cell of the aged, obese rat.In vitro insulin resistance of human adipocytes isolated from subjects with noninsulin-dependent diabetes mellitus.Transcriptional regulation of the insulin-responsive glucose transporter GLUT4 gene: from physiology to pathology.Correction of hyperglycemia with phloridzin restores the glucagon response to glucose in insulin-deficient dogs: implications for human diabetes.Permeability of ocular vessels and transport across the blood-retinal-barrier.Free fatty acids repress the GLUT4 gene expression in cardiac muscle via novel response elements.The biochemistry of diabetes.Effect of streptozotocin-induced diabetes on GLUT-4 phosphorylation in rat adipocytes.Effect of insulin on the rates of synthesis and degradation of GLUT1 and GLUT4 glucose transporters in 3T3-L1 adipocytes.Treatment of streptozotocin-diabetic rats with metformin restores the ability of insulin to inhibit adenylate cyclase activity and demonstrates that insulin does not exert this action through the inhibitory guanine nucleotide regulatory protein Gi.Alterations of glucose transporter systems in insulin-resistant uremic rats.Exercise training increases the number of glucose transporters in rat adipose cells.Effect of diabetes and fasting on GLUT-4 (muscle/fat) glucose-transporter expression in insulin-sensitive tissues. Heterogeneous response in heart, red and white muscle.Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect.Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport.Expression of constitutively activated Gialpha2 in vivo ameliorates streptozotocin-induced diabetes.Postreceptor defect in insulin action in streptozotocin-induced diabetic rats.Autophosphorylation and kinase activity of insulin receptor in diabetic rats.Molecular Biology as a Tool in the Study of Glucose Transport and Metabolism
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P2860
A possible mechanism of insulin resistance in the rat adipose cell in streptozotocin-induced diabetes mellitus. Depletion of intracellular glucose transport systems
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1981
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
A possible mechanism of insuli ...... ular glucose transport systems
@en
A possible mechanism of insuli ...... lar glucose transport systems.
@nl
type
label
A possible mechanism of insuli ...... ular glucose transport systems
@en
A possible mechanism of insuli ...... lar glucose transport systems.
@nl
prefLabel
A possible mechanism of insuli ...... ular glucose transport systems
@en
A possible mechanism of insuli ...... lar glucose transport systems.
@nl
P2093
P2860
P356
P1476
A possible mechanism of insuli ...... ular glucose transport systems
@en
P2093
P2860
P304
P356
10.1172/JCI110318
P407
P577
1981-09-01T00:00:00Z