Retinal degeneration is rescued in transgenic rd mice by expression of the cGMP phosphodiesterase beta subunit.
about
Onconeural antigens and the paraneoplastic neurologic disorders: at the intersection of cancer, immunity, and the brainDawn of ocular gene therapy: implications for molecular diagnosis in retinal diseaseNegative regulation of the novel norpA(P24) suppressor, diehard4, in the endo-lysosomal trafficking underlies photoreceptor cell degenerationThirty distinct CACNA1F mutations in 33 families with incomplete type of XLCSNB and Cacna1f expression profiling in mouse retinaPhototransduction in transgenic mice after targeted deletion of the rod transducin alpha -subunitRetinal projections in mice with inherited retinal degeneration: implications for circadian photoentrainment.Engineering retina from human retinal progenitors (cell lines).An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration.Correction of the retinal dystrophy phenotype of the RCS rat by viral gene transfer of Mertk.Rhodopsin-regulated insulin receptor signaling pathway in rod photoreceptor neurons.Pathways to photoreceptor cell death in inherited retinal degenerations.Rod photoreceptor-specific gene expression in human retinoblastoma cells.shRNA knockdown of guanylate cyclase 2e or cyclic nucleotide gated channel alpha 1 increases photoreceptor survival in a cGMP phosphodiesterase mouse model of retinitis pigmentosaPhotoreceptor cell apoptosis in the retinal degeneration of Uchl3-deficient mice.Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse.Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase.Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus.Gene therapy provides long-term visual function in a pre-clinical model of retinitis pigmentosaStable and efficient gene transfer into the retina using an HIV-based lentiviral vector.Non-invasive gene transfer by iontophoresis for therapy of an inherited retinal degenerationCell loss in retinal dystrophies by apoptosis--death by informed consent!Naturally occurring animal models with outer retina phenotypes.Rescue from photoreceptor degeneration in the rd mouse by human immunodeficiency virus vector-mediated gene transfer.Cre-mediated somatic site-specific recombination in mice.Use of a retroviral vector with an internal opsin promoter to direct gene expression to retinal photoreceptor cells.Encapsidated adenovirus mini-chromosome-mediated delivery of genes to the retina: application to the rescue of photoreceptor degeneration.Next-generation sequencing revealed a novel mutation in the gene encoding the beta subunit of rod phosphodiesterase.In vivo regulation of phosphoinositide 3-kinase in retina through light-induced tyrosine phosphorylation of the insulin receptor beta-subunit.Persistent hyperplastic tunica vasculosa lentis and persistent hyperplastic primary vitreous in transgenic line TgN3261Rpw.Evaluation of recombinant adeno-associated virus as a gene transfer vector for the retina.Polyplex-mediated gene transfer into human retinal pigment epithelial cells in vitro.Animal models of human retinal dystrophies.
P2860
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P2860
Retinal degeneration is rescued in transgenic rd mice by expression of the cGMP phosphodiesterase beta subunit.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1992
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Retinal degeneration is rescue ...... hosphodiesterase beta subunit.
@en
Retinal degeneration is rescue ...... hosphodiesterase beta subunit.
@nl
type
label
Retinal degeneration is rescue ...... hosphodiesterase beta subunit.
@en
Retinal degeneration is rescue ...... hosphodiesterase beta subunit.
@nl
prefLabel
Retinal degeneration is rescue ...... hosphodiesterase beta subunit.
@en
Retinal degeneration is rescue ...... hosphodiesterase beta subunit.
@nl
P2093
P2860
P356
P1476
Retinal degeneration is rescue ...... hosphodiesterase beta subunit.
@en
P2093
P2860
P304
P356
10.1073/PNAS.89.10.4422
P407
P577
1992-05-01T00:00:00Z