Enzymic basis for cyclic GMP accumulation in degenerative photoreceptor cells of mouse retina
about
Mutation spectrum of the gene encoding the beta subunit of rod phosphodiesterase among patients with autosomal recessive retinitis pigmentosaGenomic organization and complete sequence of the human gene encoding the beta-subunit of the cGMP phosphodiesterase and its localisation to 4p 16.3Biology and therapy of inherited retinal degenerative disease: insights from mouse modelsReview: the history and role of naturally occurring mouse models with Pde6b mutationsIn vivo studies of the gamma subunit of retinal cGMP-phophodiesterase with a substitution of tyrosine-84Induction of heme oxygenase 1 in the retina by intense visible light: suppression by the antioxidant dimethylthioureaMolecular genetics of retinitis pigmentosaDominant cone-rod dystrophy: a mouse model generated by gene targeting of the GCAP1/Guca1a gene.Phototransduction in mouse rods and cones.Isolation of a candidate cDNA for the gene causing retinal degeneration in the rd mouse.A truncated form of rod photoreceptor PDE6 β-subunit causes autosomal dominant congenital stationary night blindness by interfering with the inhibitory activity of the γ-subunit.General pathophysiology in retinal degeneration.A null mutation in the photoreceptor guanylate cyclase gene causes the retinal degeneration chicken phenotype.Variable phenotypic expressivity in inbred retinal degeneration mouse lines: A comparative study of C3H/HeOu and FVB/N rd1 micePCR analysis of DNA from 70-year-old sections of rodless retina demonstrates identity with the mouse rd defectAAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation.Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene.In vivo imaging of the photoreceptor mosaic in retinal dystrophies and correlations with visual function.A novel mutation and phenotypes in phosphodiesterase 6 deficiency.Retinal degeneration is rescued in transgenic rd mice by expression of the cGMP phosphodiesterase beta subunit.Functional rescue of degenerating photoreceptors in mice homozygous for a hypomorphic cGMP phosphodiesterase 6 b allele (Pde6bH620Q).Transgenic mice carrying the H258N mutation in the gene encoding the beta-subunit of phosphodiesterase-6 (PDE6B) provide a model for human congenital stationary night blindness.Retinal degeneration in mice lacking the gamma subunit of the rod cGMP phosphodiesterase.Calcium and cyclic nucleotide regulation in incubated mouse retinas.Silencing of tuberin enhances photoreceptor survival and function in a preclinical model of retinitis pigmentosa (an american ophthalmological society thesis).Molecular advances in retinitis pigmentosaCyclic GMP phosphodiesterase from bovine retina. Evidence for interspecies conservation.
P2860
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P2860
Enzymic basis for cyclic GMP accumulation in degenerative photoreceptor cells of mouse retina
description
1976 nî lūn-bûn
@nan
1976 թուականին հրատարակուած գիտական յօդուած
@hyw
1976 թվականին հրատարակված գիտական հոդված
@hy
1976年の論文
@ja
1976年論文
@yue
1976年論文
@zh-hant
1976年論文
@zh-hk
1976年論文
@zh-mo
1976年論文
@zh-tw
1976年论文
@wuu
name
Enzymic basis for cyclic GMP a ...... receptor cells of mouse retina
@ast
Enzymic basis for cyclic GMP a ...... receptor cells of mouse retina
@en
Enzymic basis for cyclic GMP a ...... receptor cells of mouse retina
@nl
type
label
Enzymic basis for cyclic GMP a ...... receptor cells of mouse retina
@ast
Enzymic basis for cyclic GMP a ...... receptor cells of mouse retina
@en
Enzymic basis for cyclic GMP a ...... receptor cells of mouse retina
@nl
prefLabel
Enzymic basis for cyclic GMP a ...... receptor cells of mouse retina
@ast
Enzymic basis for cyclic GMP a ...... receptor cells of mouse retina
@en
Enzymic basis for cyclic GMP a ...... receptor cells of mouse retina
@nl
P1476
Enzymic basis for cyclic GMP a ...... receptor cells of mouse retina
@en
P2093
D B Farber
R N Lolley
P304
P407
P577
1976-01-01T00:00:00Z