Impairing the mitochondrial fission and fusion balance: a new mechanism of neurodegeneration.
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The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicityChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial functionMolecular and biochemical trajectories from diabetes to Alzheimer's disease: A critical appraisalMitochondrial dysfunction in psychiatric morbidity: current evidence and therapeutic prospectsPhysiological and pathological significance of dynamin-related protein 1 (drp1)-dependent mitochondrial fission in the nervous systemQuality matters: how does mitochondrial network dynamics and quality control impact on mtDNA integrity?Mitochondrial dysfunction and oxidative stress in Parkinson's diseaseThe i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fissionMitochondrial fission proteins in peripheral blood lymphocytes are potential biomarkers for Alzheimer's diseaseVimar Is a Novel Regulator of Mitochondrial Fission through MiroMitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration mice reveals a role for Nna proteins in neuronal bioenergeticsMitochondrial therapy for Parkinson's disease: neuroprotective pharmaconutrition may be disease-modifyingNew insights into mitochondrial structure during cell death.Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization.DJ-1 knock-down impairs astrocyte mitochondrial function.Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: relevance to lung cancerIncreased optic atrophy type 1 expression protects retinal ganglion cells in a mouse model of glaucoma.Pathophysiology of autism spectrum disorders: revisiting gastrointestinal involvement and immune imbalanceAbnormalities in mitochondrial structure in cells from patients with bipolar disorder.Mitochondrial loss, dysfunction and altered dynamics in Huntington's diseaseDJ-1 null dopaminergic neuronal cells exhibit defects in mitochondrial function and structure: involvement of mitochondrial complex I assemblyDeceleration of fusion-fission cycles improves mitochondrial quality control during aging.Mucuna pruriens (Velvet bean) rescues motor, olfactory, mitochondrial and synaptic impairment in PINK1B9 Drosophila melanogaster genetic model of Parkinson's disease.Mitochondrial dynamics in diabetes.TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expressionMitochondrial fission and autophagy in the normal and diseased heartEvidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions.Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activityMitochondrial fission augments capsaicin-induced axonal degenerationPGC-1α activity in nigral dopamine neurons determines vulnerability to α-synucleinMutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's diseaseDiabetic retinopathy and damage to mitochondrial structure and transport machinery.Altered Mitochondrial Dynamics Contributes to Propofol-induced Cell Death in Human Stem Cell-derived Neurons.Serum Response Factor (SRF)-cofilin-actin signaling axis modulates mitochondrial dynamics.Natural variation in Caenorhabditis briggsae mitochondrial form and function suggests a novel model of organelle dynamics.Downregulation of Pink1 influences mitochondrial fusion-fission machinery and sensitizes to neurotoxins in dopaminergic cells.Altered Mitochondrial Dynamics and TBI Pathophysiology.Ubisol-Q10 Prevents Glutamate-Induced Cell Death by Blocking Mitochondrial Fragmentation and Permeability Transition Pore OpeningMonitoring mitophagy in neuronal cell cultures.Mitochondrial elongation in the macular RPE of aging monkeys, evidence of metabolic stress.
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Impairing the mitochondrial fission and fusion balance: a new mechanism of neurodegeneration.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Impairing the mitochondrial fi ...... echanism of neurodegeneration.
@en
Impairing the mitochondrial fi ...... echanism of neurodegeneration.
@nl
type
label
Impairing the mitochondrial fi ...... echanism of neurodegeneration.
@en
Impairing the mitochondrial fi ...... echanism of neurodegeneration.
@nl
prefLabel
Impairing the mitochondrial fi ...... echanism of neurodegeneration.
@en
Impairing the mitochondrial fi ...... echanism of neurodegeneration.
@nl
P2860
P356
P1476
Impairing the mitochondrial fi ...... echanism of neurodegeneration.
@en
P2093
Andrew B Knott
Ella Bossy-Wetzel
P2860
P304
P356
10.1196/ANNALS.1427.030
P407
P577
2008-12-01T00:00:00Z