Increased tumorigenicity and sensitivity to ionizing radiation upon loss of chromosomal protein HMGN1. - Wikidata - wikimedia - TriplyDB

Increased tumorigenicity and sensitivity to ionizing radiation upon loss of chromosomal protein HMGN1.

Increased tumorigenicity and sensitivity to ionizing radiation upon loss of chromosomal protein HMGN1.

http://www.wikidata.org/entity/Q37021730

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Downregulation of the nucleosome-binding protein 1 (NSBP1) gene can inhibit the in vitro and in vivo proliferation of prostate cancer cells Three-color FISH analysis of TMPRSS2/ERG fusions in prostate cancer indicates that genomic microdeletion of chromosome 21 is associated with rearrangement Metabolomics reveals a role for the chromatin-binding protein HMGN5 in glutathione metabolism HMGN1 protein regulates poly(ADP-ribose) polymerase-1 (PARP-1) self-PARylation in mouse fibroblasts The nucleosome binding protein HMGN3 is expressed in pancreatic alpha-cells and affects plasma glucagon levels in mice Effects of HMGN variants on the cellular transcription profile High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner.Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer.HMGN5/NSBP1: a new member of the HMGN protein family that affects chromatin structure and function Developmental function of HMGN proteins Regulation of chromatin structure and function by HMGN proteins.HMGNs, DNA repair and cancer.HMGN2, a new anti-tumor effector molecule of CD8⁺ T cells.Down-regulation of nucleosomal binding protein HMGN1 expression during embryogenesis modulates Sox9 expression in chondrocytes.HMGB1 in health and disease.Evolution of high mobility group nucleosome-binding proteins and its implications for vertebrate chromatin specialization.Distinct properties of human HMGN5 reveal a rapidly evolving but functionally conserved nucleosome binding protein.High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.The nucleosome binding protein HMGN1 interacts with PCNA and facilitates its binding to chromatin.HMGN proteins modulate chromatin regulatory sites and gene expression during activation of naïve B cells.The HMGN family of chromatin-binding proteins: dynamic modulators of epigenetic processes.Nucleosome binding proteins potentiate ATM activation and DNA damage response by modifying chromatin The nucleosome-binding protein HMGN2 modulates global genome repair HMGN1 modulates estrogen-mediated transcriptional activation through interactions with specific DNA-binding transcription factors.Delineation of the protein module that anchors HMGN proteins to nucleosomes in the chromatin of living cells HMG chromosomal proteins in development and disease.Chromosomal protein HMGN1 enhances the heat shock-induced remodeling of Hsp70 chromatin Hmgn1 acts downstream of C/EBPβ to regulate the decidualization of uterine stromal cells in mice.HMGN1 modulates nucleosome occupancy and DNase I hypersensitivity at the CpG island promoters of embryonic stem cells.Activation of ATM depends on chromatin interactions occurring before induction of DNA damage Nucleosome-binding protein HMGN2 exhibits antitumor activity in oral squamous cell carcinoma.E2F1 coregulates cell cycle genes and chromatin components during the transition of oligodendrocyte progenitors from proliferation to differentiation.Loss of the nucleosome-binding protein HMGN1 affects the rate of N-nitrosodiethylamine-induced hepatocarcinogenesis in mice.Nuclear functions of the HMG proteins.Chromatin and the DNA damage response: the cancer connection.Elevated HMGN4 expression potentiates thyroid tumorigenesis.The high-mobility group nucleosome-binding domain 5 is highly expressed in breast cancer and promotes the proliferation and invasion of breast cancer cells.HMGN5 knockdown sensitizes prostate cancer cells to ionizing radiation.High-mobility group nucleosome-binding protein 1 is a novel clinical biomarker in non-small cell lung cancer.Therapeutic vaccine to cure large mouse hepatocellular carcinomas.

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Increased tumorigenicity and sensitivity to ionizing radiation upon loss of chromosomal protein HMGN1.

http://www.wikidata.org/entity/Q37021730

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on August 2005

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Increased tumorigenicity and s ...... of chromosomal protein HMGN1.

@en

Increased tumorigenicity and s ...... of chromosomal protein HMGN1.

@nl

type

label

Increased tumorigenicity and s ...... of chromosomal protein HMGN1.

@en

Increased tumorigenicity and s ...... of chromosomal protein HMGN1.

@nl

prefLabel

Increased tumorigenicity and s ...... of chromosomal protein HMGN1.

@en

Increased tumorigenicity and s ...... of chromosomal protein HMGN1.

@nl

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0008-5472.CAN-05-0310

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Cancer Research

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Increased tumorigenicity and s ...... of chromosomal protein HMGN1.

@en

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Diana C Haines

http://www.w3.org/2001/XMLSchema#string

Frédéric Catez

http://www.w3.org/2001/XMLSchema#string

Jae-Hwan Lim

http://www.w3.org/2001/XMLSchema#string

Katherine L West

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Marta Prymakowska-Bosak

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Michael Bustin

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Takashi Furusawa

http://www.w3.org/2001/XMLSchema#string

Yehudit Birger

http://www.w3.org/2001/XMLSchema#string

Yuri V Postnikov

http://www.w3.org/2001/XMLSchema#string

P2860

Stimulation of RNA polymerase II elongation by chromosomal protein HMG-14

Mitotic phosphorylation prevents the binding of HMGN proteins to chromatin

Megabase chromatin domains involved in DNA double-strand breaks in vivo

The DNA damage response: putting checkpoints in perspective

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Histone H2A variants H2AX and H2AZ

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

Cell-cycle checkpoints and cancer

Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin

Genomic instability in mice lacking histone H2AX

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6711-6718

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scholarly article

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10.1158/0008-5472.CAN-05-0310

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15

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2005-08-01T00:00:00Z

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16061652

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3714215

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