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Activation of ATM depends on chromatin interactions occurring before induction of DNA damage

Activation of ATM depends on chromatin interactions occurring before induction of DNA damage

http://www.wikidata.org/entity/Q37280637

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Radiation-induced alterations in histone modification patterns and their potential impact on short-term radiation effects Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1 VRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damage PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair DNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosis RNA polymerase II termination involves C-terminal-domain tyrosine dephosphorylation by CPF subunit Glc7 Stemness factor Sall4 is required for DNA damage response in embryonic stem cells HMGN1 protein regulates poly(ADP-ribose) polymerase-1 (PARP-1) self-PARylation in mouse fibroblasts The nucleosome binding protein HMGN3 is expressed in pancreatic alpha-cells and affects plasma glucagon levels in mice Effects of HMGN variants on the cellular transcription profile Involvement of GLTSCR2 in the DNA Damage Response.High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner.HMGN5/NSBP1: a new member of the HMGN protein family that affects chromatin structure and function HMG modifications and nuclear function.Developmental function of HMGN proteins Regulation of chromatin structure and function by HMGN proteins.Mediator of DNA damage checkpoint 1 (MDC1) contributes to high NaCl-induced activation of the osmoprotective transcription factor TonEBP/OREBP.Chromatin at the intersection of viral infection and DNA damage HMGNs, DNA repair and cancer.ATM modulates transcription in response to histone deacetylase inhibition as part of its DNA damage response.Analysis of individual molecular events of DNA damage response by flow- and image-assisted cytometry Higher-order genome organization in human disease The versatile functions of ATM kinase.Modeling the basal dynamics of p53 system.Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance Chromatin remodeling, DNA damage repair and aging.ATM signalling and cancer.UV-induced histone H2AX phosphorylation and DNA damage related proteins accumulate and persist in nucleotide excision repair-deficient XP-B cells TOPLESS mediates brassinosteroid-induced transcriptional repression through interaction with BZR1 The 53BP1-EXPAND1 connection in chromatin structure regulation.Evolution of high mobility group nucleosome-binding proteins and its implications for vertebrate chromatin specialization.Chfr and RNF8 synergistically regulate ATM activation.Distinct properties of human HMGN5 reveal a rapidly evolving but functionally conserved nucleosome binding protein.Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair 'Relax and Repair' to restrain aging.Histone H3 lysine 14 acetylation is required for activation of a DNA damage checkpoint in fission yeast.The nucleosome binding protein HMGN1 interacts with PCNA and facilitates its binding to chromatin.Chromatin dynamics in DNA double-strand break repair The HMGN family of chromatin-binding proteins: dynamic modulators of epigenetic processes.Nucleosome binding proteins potentiate ATM activation and DNA damage response by modifying chromatin

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Activation of ATM depends on chromatin interactions occurring before induction of DNA damage

http://www.wikidata.org/entity/Q37280637

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 14 December 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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Activation of ATM depends on c ...... before induction of DNA damage

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Activation of ATM depends on c ...... efore induction of DNA damage.

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Activation of ATM depends on c ...... before induction of DNA damage

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Activation of ATM depends on c ...... efore induction of DNA damage.

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Activation of ATM depends on c ...... before induction of DNA damage

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Activation of ATM depends on c ...... efore induction of DNA damage.

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Nature Cell Biology

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Activation of ATM depends on c ...... before induction of DNA damage

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Andre Nussenzweig

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Kyu-Seon Oh

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Michael Bustin

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Takashi Furusawa

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Yong-Chul Kim

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Yosef Shiloh

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MDC1 is a mediator of the mammalian DNA damage checkpoint

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

Genome maintenance mechanisms for preventing cancer

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

MDC1 is required for the intra-S-phase DNA damage checkpoint

HMG proteins: dynamic players in gene regulation and differentiation

A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM

Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin

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scholarly article

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10.1038/NCB1817

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1

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11

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Kenneth H Kraemer

Frédéric Catez

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2008-12-14T00:00:00Z

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23660086

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19079244

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2717731

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