Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile
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Mitochondrial Quality Control and Muscle Mass MaintenanceLong live FOXO: unraveling the role of FOXO proteins in aging and longevityRedox regulation of FoxO transcription factorsOptimal body weight for health and longevity: bridging basic, clinical, and population researchThe search for antiaging interventions: from elixirs to fasting regimensNLRP3 inflammasome and its inhibitors: a reviewCardioprotective Signature of Short-Term Caloric RestrictionDietary and pharmacological modification of the insulin/IGF-1 system: exploiting the full repertoire against cancerLongevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intakeSex- and tissue-specific changes in mTOR signaling with age in C57BL/6J miceThe Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and AgingEffect of solvents extraction on phytochemical components and biological activities of Tunisian date seeds (var. Korkobbi and Arechti).NutrimiRAging: Micromanaging Nutrient Sensing Pathways through Nutrition to Promote Healthy Aging.Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue.AMPK activation: a therapeutic target for type 2 diabetes?Akt phosphorylation and regulation of transketolase is a nodal point for amino acid control of purine synthesisWill calorie restriction work in humans?Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population.Epigenetic linkage of aging, cancer and nutrition.Diminished mTOR signaling: a common mode of action for endocrine longevity factors.Promoting health and longevity through diet: from model organisms to humans.Age-associated changes in basal NF-κB function in human CD4+ T lymphocytes via dysregulation of PI3 kinase.Nitric oxide, interorganelle communication, and energy flow: a novel route to slow aging.Caloric restriction reveals a metabolomic and lipidomic signature in liver of male miceThe ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory diseaseIn vitro caloric restriction induces protective genes and functional rejuvenation in senescent SAMP8 astrocytes.Frailty in childhood cancer survivors.Caloric restriction induces heat shock response and inhibits B16F10 cell tumorigenesis both in vitro and in vivoImmune aging, dysmetabolism, and inflammation in neurological diseases.Curcumin enhances parental reproductive lifespan and progeny viability in Drosophila melanogaster.Independent chemical regulation of health and senescent spans in DrosophilaDeriving a cardiac ageing signature to reveal MMP-9-dependent inflammatory signalling in senescence.The mitochondrial uncoupler DNP triggers brain cell mTOR signaling network reprogramming and CREB pathway up-regulationAssociation of Geroprotective Effects of Metformin and Risk of Open-Angle Glaucoma in Persons With Diabetes Mellitus.Age-Related Neurodegeneration Prevention Through mTOR Inhibition: Potential Mechanisms and Remaining Questions.A Genetic Network Associated With Stress Resistance, Longevity, and Cancer in Humans.The effects of graded levels of calorie restriction: VI. Impact of short-term graded calorie restriction on transcriptomic responses of the hypothalamic hunger and circadian signaling pathways.Differences in genome-wide gene expression response in peripheral blood mononuclear cells between young and old men upon caloric restriction.Transgenic overexpression of VEGF-C induces weight gain and insulin resistance in mice.Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models
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Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 05 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Calorie restriction in humans ...... younger transcription profile
@en
Calorie restriction in humans ...... younger transcription profile.
@nl
type
label
Calorie restriction in humans ...... younger transcription profile
@en
Calorie restriction in humans ...... younger transcription profile.
@nl
prefLabel
Calorie restriction in humans ...... younger transcription profile
@en
Calorie restriction in humans ...... younger transcription profile.
@nl
P2093
P2860
P50
P356
P1433
P1476
Calorie restriction in humans ...... younger transcription profile
@en
P2093
Claudio Franceschi
Dennis T Villareal
Evi M Mercken
Lellean JeBailey
Seth D Crosby
Susan Krzysik-Walker
Yongqing Zhang
P2860
P304
P356
10.1111/ACEL.12088
P577
2013-06-05T00:00:00Z