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Genetics of Human and Canine Dilated CardiomyopathyContractile apparatus dysfunction early in the pathophysiology of diabetic cardiomyopathyTop-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failureSarcomeric protein isoform transitions in cardiac muscle: a journey to heart failureProtein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardiumCardiac thin filament regulationPhosphorylation of tropomyosin extends cooperative binding of myosin beyond a single regulatory unitA 2-D gel reference map of the basic human heart proteome.Thin filament incorporation of an engineered cardiac troponin C variant (L48Q) enhances contractility in intact cardiomyocytes from healthy and infarcted hearts.Cardiac troponin T, a sarcomeric AKAP, tethers protein kinase A at the myofilaments.What we know and do not know about sex and cardiac disease.Attenuated fatigue in slow twitch skeletal muscle during isotonic exercise in rats with chronic heart failure.Measuring the contractile forces of human induced pluripotent stem cell-derived cardiomyocytes with arrays of micropostsDCM-related tropomyosin mutants E40K/E54K over-inhibit the actomyosin interaction and lead to a decrease in the number of cycling cross-bridges.Top-down mass spectrometry of cardiac myofilament proteins in health and disease.Enhanced active cross-bridges during diastole: molecular pathogenesis of tropomyosin's HCM mutationsMyofilament calcium sensitization delays decompensated hypertrophy differently between the sexes following myocardial infarctionDeciphering modifications in swine cardiac troponin I by top-down high-resolution tandem mass spectrometry.Signaling to myosin regulatory light chain in sarcomeresDiastolic myofilament dysfunction in the failing human heart.Beneficial effects of SR33805 in failing myocardium.Biochemical and myofilament responses of the right ventricle to severe pulmonary hypertension.In vivo phosphorylation site mapping in mouse cardiac troponin I by high resolution top-down electron capture dissociation mass spectrometry: Ser22/23 are the only sites basally phosphorylated.ACE inhibition prevents diastolic Ca2+ overload and loss of myofilament Ca2+ sensitivity after myocardial infarction.ADP-stimulated contraction: A predictor of thin-filament activation in cardiac disease.Anchoring proteins as regulators of signaling pathways.Myocyte shape regulates lateral registry of sarcomeres and contractility.Contractile protein phosphorylation predicts human heart disease phenotypesTroponin phosphorylation and myofilament Ca2+-sensitivity in heart failure: increased or decreased?A gain-of-function mutation in the M-domain of cardiac myosin-binding protein-C increases binding to actin.Multiplex kinase signaling modifies cardiac function at the level of sarcomeric proteins.Cardiac metabolism in heart failure: implications beyond ATP production.Mechanotransduction and Metabolism in Cardiomyocyte Microdomains.Divide and conquer: the application of organelle proteomics to heart failure.Characterization and validation of new tools for measuring site-specific cardiac troponin I phosphorylation.Stk38 Modulates Rbm24 Protein Stability to Regulate Sarcomere Assembly in Cardiomyocytes.Maladaptive modifications in myofilament proteins and triggers in the progression to heart failure and sudden death.Exercise training in adverse cardiac remodeling.Cardiac tissue structure, properties, and performance: a materials science perspective.Chronic heart failure: Ca(2+), catabolism, and catastrophic cell death.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Sarcomeric dysfunction in heart failure.
@en
Sarcomeric dysfunction in heart failure.
@nl
type
label
Sarcomeric dysfunction in heart failure.
@en
Sarcomeric dysfunction in heart failure.
@nl
prefLabel
Sarcomeric dysfunction in heart failure.
@en
Sarcomeric dysfunction in heart failure.
@nl
P2093
P50
P356
P1476
Sarcomeric dysfunction in heart failure
@en
P2093
Cris Dos Remedios
Dirk J Duncker
Nazha Hamdani
Sabine van Dijk
Viola Kooij
Walter J Paulus
P304
P356
10.1093/CVR/CVM079
P577
2007-11-30T00:00:00Z