Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage. - Wikidata - wikimedia - TriplyDB

Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage.

Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage.

http://www.wikidata.org/entity/Q37023057

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Therapeutic interventions against inflammatory and angiogenic mediators in proliferative diabetic retinopathy Rho kinase proteins--pleiotropic modulators of cell survival and apoptosis ER stress and apoptosis: a new mechanism for retinal cell death.Information exploration system for sickle cell disease and repurposing of hydroxyfasudil Oxidative Stress-Related Mechanisms and Antioxidant Therapy in Diabetic Retinopathy Molecular Imaging of Retinal Endothelial Injury in Diabetic Animals.The role of rho kinase in sex-dependent vascular dysfunction in type 1 diabetes.Gene variations of ROCKs and risk of ischaemic stroke: the Women's Genome Health Study.Involvement of RhoA/ROCK1 signaling pathway in hyperglycemia-induced microvascular endothelial dysfunction in diabetic retinopathy Aberrant ROCK activation promotes the development of type I diabetes in NOD mice Activation of ErbB2 and Downstream Signalling via Rho Kinases and ERK1/2 Contributes to Diabetes-Induced Vascular Dysfunction.Complex regulation of PKCβ2 and PDK-1/AKT by ROCK2 in diabetic heart.Wound contraction is attenuated by fasudil inhibition of Rho-associated kinase The Rho kinase inhibitor Y-27632 increases erythrocyte deformability and low oxygen tension-induced ATP release.Fasudil hydrochloride, a potent ROCK inhibitor, inhibits corneal neovascularization after alkali burns in mice Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study.Elevated Glucose Levels Promote Contractile and Cytoskeletal Gene Expression in Vascular Smooth Muscle via Rho/Protein Kinase C and Actin Polymerization RhoA/rock signaling mediates peroxynitrite-induced functional impairment of Rat coronary vessels Blocking VEGF/Caveolin-1 signaling contributes to renal protection of fasudil in streptozotocin-induced diabetic rats ROCK inhibitor fasudil attenuated high glucose-induced MCP-1 and VCAM-1 expression and monocyte-endothelial cell adhesion Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm's canal endothelial cells.Diabetes causes bone marrow endothelial barrier dysfunction by activation of the RhoA-Rho-associated kinase signaling pathway.Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout.Acute Rho-kinase inhibition improves coronary dysfunction in vivo, in the early diabetic microcirculation ROCK1 reduces mitochondrial content and irisin production in muscle suppressing adipocyte browning and impairing insulin sensitivity.Lymphoblastoid Cell Lines as a Tool to Study Inter-Individual Differences in the Response to Glucose The Rho/Rho-associated protein kinase inhibitor fasudil in the protection of endothelial cells against advanced glycation end products through the nuclear factor κB pathway.Thromboxane A2 receptor activates a Rho-associated kinase/LKB1/PTEN pathway to attenuate endothelium insulin signaling.Targeting of Rho kinase ameliorates impairment of diabetic endothelial function in intrarenal artery.The Andes Virus Nucleocapsid Protein Directs Basal Endothelial Cell Permeability by Activating RhoA.Molecular mechanisms of endothelial hyperpermeability: implications in inflammation.ROCK-isoform-specific polarization of macrophages associated with age-related macular degeneration.Endothelial contractile cytoskeleton and microvascular permeability.Long-term diabetic complications may be ameliorated by targeting Rho kinase.Inflammation in diabetic retinopathy.Acute and sustained actions of hyperglycaemia on endothelial and glomerular barrier permeability.Targeting endothelial dysfunction in vascular complications associated with diabetes.Rho-kinase inhibitors offer a new approach in the treatment of glaucoma.Intravitreal fasudil combined with bevacizumab for treatment of refractory diabetic macular edema; a pilot study.RhoA/mDia-1/profilin-1 signaling targets microvascular endothelial dysfunction in diabetic retinopathy.

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Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage.

http://www.wikidata.org/entity/Q37023057

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 07 October 2008

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

@da

vědecký článek

@cs

name

Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage.

@en

Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage.

@nl

type

label

Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage.

@en

Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage.

@nl

prefLabel

Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage.

@en

Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage.

@nl

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Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage.

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Ali Hafezi-Moghadam

http://www.w3.org/2001/XMLSchema#string

Faryan Tayyari

http://www.w3.org/2001/XMLSchema#string

Hiroaki Shimokawa

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Lama Almulki

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Muneki Miura

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Ryoichi Arita

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Shintaro Nakao

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Shuhei Kawahara

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Souska Zandi

http://www.w3.org/2001/XMLSchema#string

Takeshi Kita

http://www.w3.org/2001/XMLSchema#string

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Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes.

Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

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Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression

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215-226

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scholarly article

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10.2337/DB08-0762

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1

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58

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2008-10-07T00:00:00Z

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23305178

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18840783

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2606876

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