Mechanical strain inhibits adipogenesis in mesenchymal stem cells by stimulating a durable beta-catenin signal. - Wikidata - wikimedia - TriplyDB

Mechanical strain inhibits adipogenesis in mesenchymal stem cells by stimulating a durable beta-catenin signal.

Mechanical strain inhibits adipogenesis in mesenchymal stem cells by stimulating a durable beta-catenin signal.

http://www.wikidata.org/entity/Q37034948

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Control of stem cell fate by physical interactions with the extracellular matrix Exercise Regulation of Marrow Adipose Tissue Bone Fragility in Turner Syndrome: Mechanisms and Prevention Strategies Physiological mechanisms and therapeutic potential of bone mechanosensing.Environmental physical cues determine the lineage specification of mesenchymal stem cells Treadmill training regulates β-catenin signaling through phosphorylation of GSK-3β in lumbar vertebrae of ovariectomized rats Uniaxial mechanical tension promoted osteogenic differentiation of rat tendon-derived stem cells (rTDSCs) via the Wnt5a-RhoA pathway Evolutionary conservation of early mesoderm specification by mechanotransduction in Bilateria Mechanical signals as anabolic agents in bone.Silk Hydrogels of Tunable Structure and Viscoelastic Properties Using Different Chronological Orders of Genipin and Physical Cross-Linking Obesity-driven disruption of haematopoiesis and the bone marrow niche.Mesenchymal stem cell mechanobiology and emerging experimental platforms.Mechanical strain modulates age-related changes in the proliferation and differentiation of mouse adipose-derived stromal cells.Bone marrow fat accumulation accelerated by high fat diet is suppressed by exercise.A flow cytometry-based screen of nuclear envelope transmembrane proteins identifies NET4/Tmem53 as involved in stress-dependent cell cycle withdrawal.The small molecule indirubin-3'-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity.Development of diet-induced fatty liver disease in the aging mouse is suppressed by brief daily exposure to low-magnitude mechanical signals.c-Maf and you won't see fat.Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone Mechanical Signals As a Non-Invasive Means to Influence Mesenchymal Stem Cell Fate, Promoting Bone and Suppressing the Fat Phenotype Exercise Regulation of Marrow Fat in the Setting of PPARγ Agonist Treatment in Female C57BL/6 Mice.Mechanical strain downregulates C/EBPβ in MSC and decreases endoplasmic reticulum stress.β-catenin directly sequesters adipocytic and insulin sensitizing activities but not osteoblastic activity of PPARγ2 in marrow mesenchymal stem cells.Mechanical signal influence on mesenchymal stem cell fate is enhanced by incorporation of refractory periods into the loading regimen.Biomechanical forces in the skeleton and their relevance to bone metastasis: biology and engineering considerations.Principles of regulation of self-renewing cell lineages.Symmetric vs. asymmetric stem cell divisions: an adaptation against cancer?Prostaglandin E₂-EP4 signaling suppresses adipocyte differentiation in mouse embryonic fibroblasts via an autocrine mechanism Effects of obesity on bone metabolism.Shear stress induced by an interstitial level of slow flow increases the osteogenic differentiation of mesenchymal stem cells through TAZ activation Changes in protein expression in two cholangiocarcinoma cell lines undergoing formation of multicellular tumor spheroids in vitro Mechanical strain regulates osteogenic and adipogenic differentiation of bone marrow mesenchymal stem cells Body composition abnormalities in long-term survivors of pediatric hematopoietic stem cell transplantation.Mechanical regulation of glycogen synthase kinase 3β (GSK3β) in mesenchymal stem cells is dependent on Akt protein serine 473 phosphorylation via mTORC2 protein.Short-term physical activity intervention decreases femoral bone marrow adipose tissue in young children: a pilot study.Dynamic Fluid Flow Mechanical Stimulation Modulates Bone Marrow Mesenchymal Stem Cells Resistance Training in Type II Diabetes Mellitus: Impact on Areas of Metabolic Dysfunction in Skeletal Muscle and Potential Impact on Bone.Gold nanoparticles promote osteogenic differentiation in human adipose-derived mesenchymal stem cells through the Wnt/β-catenin signaling pathway Mechanical regulation of signaling pathways in bone.Update on Wnt signaling in bone cell biology and bone disease.

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Mechanical strain inhibits adipogenesis in mesenchymal stem cells by stimulating a durable beta-catenin signal.

http://www.wikidata.org/entity/Q37034948

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

@tr

scientific article published on 07 August 2008

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

@da

vědecký článek

@cs

name

Mechanical strain inhibits adi ...... a durable beta-catenin signal.

@en

Mechanical strain inhibits adi ...... a durable beta-catenin signal.

@nl

type

label

Mechanical strain inhibits adi ...... a durable beta-catenin signal.

@en

Mechanical strain inhibits adi ...... a durable beta-catenin signal.

@nl

prefLabel

Mechanical strain inhibits adi ...... a durable beta-catenin signal.

@en

Mechanical strain inhibits adi ...... a durable beta-catenin signal.

@nl

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Mechanical strain inhibits adi ...... a durable beta-catenin signal.

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P2093

Buer Sen

http://www.w3.org/2001/XMLSchema#string

Clinton Rubin

http://www.w3.org/2001/XMLSchema#string

Janet Rubin

http://www.w3.org/2001/XMLSchema#string

Meiyun Ma

http://www.w3.org/2001/XMLSchema#string

Natasha Case

http://www.w3.org/2001/XMLSchema#string

Zhihui Xie

http://www.w3.org/2001/XMLSchema#string

P2860

Patients with high bone mass phenotype exhibit enhanced osteoblast differentiation and inhibition of adipogenesis of human mesenchymal stem cells

Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Multilineage potential of adult human mesenchymal stem cells

The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment

Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation

Cancer cell cycles

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

Adipogenesis is inhibited by brief, daily exposure to high-frequency, extremely low-magnitude mechanical signals

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6065-6075

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scholarly article

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10.1210/EN.2008-0687

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12

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23156580

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18687779

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2613068

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